3ngc

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ngc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_nicotinovorans Arthrobacter nicotinovorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NGC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NGC FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ngc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_nicotinovorans Arthrobacter nicotinovorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NGC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NGC FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GP7:(1R)-2-{[(S)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTADECANOYLOXY)METHYL]ETHYL+(12E)-HEXADECA-9,12-DIENOATE'>GP7</scene>, <scene name='pdbligand=HNH:5-(1-METHYL-4,5-DIHYDRO-1H-PYRROL-2-YL)PYRIDIN-2-OL'>HNH</scene>, <scene name='pdbligand=HNL:5-[(2S)-1-METHYLPYRROLIDIN-2-YL]PYRIDIN-2-OL'>HNL</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GP7:(1R)-2-{[(S)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTADECANOYLOXY)METHYL]ETHYL+(12E)-HEXADECA-9,12-DIENOATE'>GP7</scene>, <scene name='pdbligand=HNH:5-(1-METHYL-4,5-DIHYDRO-1H-PYRROL-2-YL)PYRIDIN-2-OL'>HNH</scene>, <scene name='pdbligand=HNL:5-[(2S)-1-METHYLPYRROLIDIN-2-YL]PYRIDIN-2-OL'>HNL</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3nh3|3nh3]], [[3nho|3nho]], [[3nk0|3nk0]], [[3nk1|3nk1]], [[3nk2|3nk2]], [[3nn0|3nn0]], [[3nn6|3nn6]], [[3k7m|3k7m]], [[3k7q|3k7q]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3nh3|3nh3]], [[3nho|3nho]], [[3nk0|3nk0]], [[3nk1|3nk1]], [[3nk2|3nk2]], [[3nn0|3nn0]], [[3nn6|3nn6]], [[3k7m|3k7m]], [[3k7q|3k7q]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">6-HLNO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=29320 Arthrobacter nicotinovorans])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">6-HLNO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=29320 Arthrobacter nicotinovorans])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(S)-6-hydroxynicotine_oxidase (S)-6-hydroxynicotine oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.3.5 1.5.3.5] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(S)-6-hydroxynicotine_oxidase (S)-6-hydroxynicotine oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.3.5 1.5.3.5] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ngc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ngc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ngc RCSB], [http://www.ebi.ac.uk/pdbsum/3ngc PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ngc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ngc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ngc RCSB], [http://www.ebi.ac.uk/pdbsum/3ngc PDBsum]</span></td></tr>
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<table>
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</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Crystal structure analysis of free and substrate-bound 6-hydroxy-L-nicotine oxidase from Arthrobacter nicotinovorans.,Kachalova GS, Bourenkov GP, Mengesdorf T, Schenk S, Maun HR, Burghammer M, Riekel C, Decker K, Bartunik HD J Mol Biol. 2010 Feb 26;396(3):785-99. Epub 2009 Dec 16. PMID:20006620<ref>PMID:20006620</ref>
Crystal structure analysis of free and substrate-bound 6-hydroxy-L-nicotine oxidase from Arthrobacter nicotinovorans.,Kachalova GS, Bourenkov GP, Mengesdorf T, Schenk S, Maun HR, Burghammer M, Riekel C, Decker K, Bartunik HD J Mol Biol. 2010 Feb 26;396(3):785-99. Epub 2009 Dec 16. PMID:20006620<ref>PMID:20006620</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Arthrobacter nicotinovorans]]
[[Category: Arthrobacter nicotinovorans]]
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[[Category: Bartunik, H D.]]
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[[Category: Bartunik, H D]]
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[[Category: Kachalova, G S.]]
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[[Category: Kachalova, G S]]
[[Category: Enanthiomeric substrate-inhibitor]]
[[Category: Enanthiomeric substrate-inhibitor]]
[[Category: Flavoenzyme]]
[[Category: Flavoenzyme]]
[[Category: Nicotine degradation]]
[[Category: Nicotine degradation]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]

Revision as of 21:58, 3 January 2015

Complex of 6-hydroxy-L-nicotine oxidase with intermediate methylmyosmine product formed during catalytic turnover

3ngc, resolution 2.25Å

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