2mj7

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{{STRUCTURE_2mj7| PDB=2mj7 | SCENE= }}
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==Solution NMR structure of beta-adaptin appendage domain of human adaptor protein complex 4 subunit beta, Northeast Structural Genomics Consortium (NESG) Target HR8998C==
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===Solution NMR structure of beta-adaptin appendage domain of human adaptor protein complex 4 subunit beta, Northeast Structural Genomics Consortium (NESG) Target HR8998C===
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<StructureSection load='2mj7' size='340' side='right' caption='[[2mj7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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== Structural highlights ==
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==Disease==
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<table><tr><td colspan='2'>[[2mj7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MJ7 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AP4B1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mj7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mj7 RCSB], [http://www.ebi.ac.uk/pdbsum/2mj7 PDBsum]</span></td></tr>
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</table>
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== Disease ==
[[http://www.uniprot.org/uniprot/AP4B1_HUMAN AP4B1_HUMAN]] Severe intellectual deficit and progressive spastic paraplegia. The disease is caused by mutations affecting the gene represented in this entry.
[[http://www.uniprot.org/uniprot/AP4B1_HUMAN AP4B1_HUMAN]] Severe intellectual deficit and progressive spastic paraplegia. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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==Function==
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[[http://www.uniprot.org/uniprot/AP4B1_HUMAN AP4B1_HUMAN]] Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
[[http://www.uniprot.org/uniprot/AP4B1_HUMAN AP4B1_HUMAN]] Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
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__TOC__
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==About this Structure==
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</StructureSection>
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[[2mj7]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJ7 OCA].
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[[Category: Human]]
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[[Category: Eletsky, A.]]
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[[Category: Eletsky, A]]
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[[Category: Everett, J K.]]
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[[Category: Everett, J K]]
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[[Category: Janjua, H.]]
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[[Category: Janjua, H]]
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[[Category: Maglaqui, M.]]
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[[Category: Maglaqui, M]]
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[[Category: Montelione, G T.]]
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[[Category: Montelione, G T]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Pederson, K.]]
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[[Category: Pederson, K]]
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[[Category: Prestegard, J H.]]
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[[Category: Prestegard, J H]]
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[[Category: Rotshteyn, D J.]]
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[[Category: Rotshteyn, D J]]
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[[Category: Shastry, R.]]
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[[Category: Shastry, R]]
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[[Category: Szyperski, T.]]
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[[Category: Szyperski, T]]
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[[Category: Xiao, R.]]
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[[Category: Xiao, R]]
[[Category: Nesg]]
[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-biology]]
[[Category: Psi-biology]]
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[[Category: Structural genomic]]
 
[[Category: Transport protein]]
[[Category: Transport protein]]

Revision as of 22:02, 3 January 2015

Solution NMR structure of beta-adaptin appendage domain of human adaptor protein complex 4 subunit beta, Northeast Structural Genomics Consortium (NESG) Target HR8998C

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