2ru7
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ru7]] is a 4 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RU7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RU7 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2ru7]] is a 4 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RU7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RU7 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2rsk|2rsk]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2rsk|2rsk]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ru7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ru7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ru7 RCSB], [http://www.ebi.ac.uk/pdbsum/2ru7 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ru7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ru7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ru7 RCSB], [http://www.ebi.ac.uk/pdbsum/2ru7 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/PRIO_BOVIN PRIO_BOVIN]] Note=Variations in PRNP are responsible of transmissible bovine spongiform encephalopathies (BSE), a class of neurodegenerative diseases that affect various mammals. These diseases are caused by abnormally folded prion proteins. BSE can be subdivided into at least three groups: classical, H-type and L-type, with the latter 2 collectively referred to as atypical BSE. Susceptibility or resistance to a BSE disease can be influenced by at least 3 factors related to the host prion protein: protein expression levels, number of octapeptide repeats, and specific polymorphisms. In cattle, as in humans, BSEs can occur as infectious, spontaneous and genetic diseases. | [[http://www.uniprot.org/uniprot/PRIO_BOVIN PRIO_BOVIN]] Note=Variations in PRNP are responsible of transmissible bovine spongiform encephalopathies (BSE), a class of neurodegenerative diseases that affect various mammals. These diseases are caused by abnormally folded prion proteins. BSE can be subdivided into at least three groups: classical, H-type and L-type, with the latter 2 collectively referred to as atypical BSE. Susceptibility or resistance to a BSE disease can be influenced by at least 3 factors related to the host prion protein: protein expression levels, number of octapeptide repeats, and specific polymorphisms. In cattle, as in humans, BSEs can occur as infectious, spontaneous and genetic diseases. | ||
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Binding of an RNA aptamer and a partial peptide of a prion protein: crucial importance of water entropy in molecular recognition.,Hayashi T, Oshima H, Mashima T, Nagata T, Katahira M, Kinoshita M Nucleic Acids Res. 2014 May 6. PMID:24803670<ref>PMID:24803670</ref> | Binding of an RNA aptamer and a partial peptide of a prion protein: crucial importance of water entropy in molecular recognition.,Hayashi T, Oshima H, Mashima T, Nagata T, Katahira M, Kinoshita M Nucleic Acids Res. 2014 May 6. PMID:24803670<ref>PMID:24803670</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Hayashi, T | + | [[Category: Hayashi, T]] |
| - | [[Category: Katahira, M | + | [[Category: Katahira, M]] |
| - | [[Category: Kinoshita, M | + | [[Category: Kinoshita, M]] |
| - | [[Category: Mashima, T | + | [[Category: Mashima, T]] |
| - | [[Category: Nagata, T | + | [[Category: Nagata, T]] |
| - | [[Category: Oshima, H | + | [[Category: Oshima, H]] |
[[Category: Alzheimer's disease]] | [[Category: Alzheimer's disease]] | ||
[[Category: Aptamer]] | [[Category: Aptamer]] | ||
Revision as of 22:24, 3 January 2015
Refined structure of RNA aptamer in complex with the partial binding peptide of prion protein
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