3q3y
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3q3y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_enterovirus_b Human enterovirus b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q3Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q3Y FirstGlance]. <br> | <table><tr><td colspan='2'>[[3q3y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_enterovirus_b Human enterovirus b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q3Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q3Y FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=PI:HYDROGENPHOSPHATE+ION'>PI</scene>, <scene name='pdbligand=XNV:ETHYL+(4R)-4-({(2S)-2-[3-{[(5-METHYL-1,2-OXAZOL-3-YL)CARBONYL]AMINO}-2-OXOPYRIDIN-1(2H)-YL]PENT-4-YNOYL}AMINO)-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE'>XNV</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=PI:HYDROGENPHOSPHATE+ION'>PI</scene>, <scene name='pdbligand=XNV:ETHYL+(4R)-4-({(2S)-2-[3-{[(5-METHYL-1,2-OXAZOL-3-YL)CARBONYL]AMINO}-2-OXOPYRIDIN-1(2H)-YL]PENT-4-YNOYL}AMINO)-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE'>XNV</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q3x|3q3x]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q3x|3q3x]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">3C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=138949 Human enterovirus B])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">3C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=138949 Human enterovirus B])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Picornain_3C Picornain 3C], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.28 3.4.22.28] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Picornain_3C Picornain 3C], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.28 3.4.22.28] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q3y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q3y RCSB], [http://www.ebi.ac.uk/pdbsum/3q3y PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q3y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q3y RCSB], [http://www.ebi.ac.uk/pdbsum/3q3y PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Structural basis for antiviral inhibition of the main protease 3C from human enterovirus 93.,Costenaro L, Kaczmarska Z, Arnan C, Janowski R, Coutard B, Sola M, Gorbalenya AE, Norder H, Canard B, Coll M J Virol. 2011 Aug 10. PMID:21835784<ref>PMID:21835784</ref> | Structural basis for antiviral inhibition of the main protease 3C from human enterovirus 93.,Costenaro L, Kaczmarska Z, Arnan C, Janowski R, Coutard B, Sola M, Gorbalenya AE, Norder H, Canard B, Coll M J Virol. 2011 Aug 10. PMID:21835784<ref>PMID:21835784</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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[[Category: Human enterovirus b]] | [[Category: Human enterovirus b]] | ||
[[Category: Picornain 3C]] | [[Category: Picornain 3C]] | ||
| - | [[Category: Arnan, C | + | [[Category: Arnan, C]] |
| - | [[Category: Canard, B | + | [[Category: Canard, B]] |
| - | [[Category: Coll, M | + | [[Category: Coll, M]] |
| - | [[Category: Costenaro, L | + | [[Category: Costenaro, L]] |
| - | [[Category: Coutard, B | + | [[Category: Coutard, B]] |
| - | [[Category: Kaczmarska, Z | + | [[Category: Kaczmarska, Z]] |
| - | [[Category: Norder, H | + | [[Category: Norder, H]] |
| - | [[Category: Sola, M | + | [[Category: Sola, M]] |
[[Category: Cysteine trypsin-like protease]] | [[Category: Cysteine trypsin-like protease]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
Revision as of 22:35, 3 January 2015
Complex structure of HEVB EV93 main protease 3C with Compound 1 (AG7404)
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