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3r2j
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3r2j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_infantum Leishmania infantum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R2J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3R2J FirstGlance]. <br> | <table><tr><td colspan='2'>[[3r2j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_infantum Leishmania infantum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R2J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3R2J FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NIO:NICOTINIC+ACID'>NIO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NIO:NICOTINIC+ACID'>NIO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LinJ01.0460 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5671 Leishmania infantum])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LinJ01.0460 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5671 Leishmania infantum])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nicotinamidase Nicotinamidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.19 3.5.1.19] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nicotinamidase Nicotinamidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.19 3.5.1.19] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3r2j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r2j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3r2j RCSB], [http://www.ebi.ac.uk/pdbsum/3r2j PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3r2j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r2j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3r2j RCSB], [http://www.ebi.ac.uk/pdbsum/3r2j PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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The Leishmania nicotinamidase is essential for NAD+ production and parasite proliferation.,Gazanion E, Garcia D, Silvestre R, Gerard C, Guichou J, Labesse G, Seveno M, Cordeiro-Da-Silva A, Ouaissi A, Sereno D, Vergnes B Mol Microbiol. 2011 Aug 8. doi: 10.1111/j.1365-2958.2011.07799.x. PMID:21819459<ref>PMID:21819459</ref> | The Leishmania nicotinamidase is essential for NAD+ production and parasite proliferation.,Gazanion E, Garcia D, Silvestre R, Gerard C, Guichou J, Labesse G, Seveno M, Cordeiro-Da-Silva A, Ouaissi A, Sereno D, Vergnes B Mol Microbiol. 2011 Aug 8. doi: 10.1111/j.1365-2958.2011.07799.x. PMID:21819459<ref>PMID:21819459</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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[[Category: Leishmania infantum]] | [[Category: Leishmania infantum]] | ||
[[Category: Nicotinamidase]] | [[Category: Nicotinamidase]] | ||
| - | [[Category: Garcia, D | + | [[Category: Garcia, D]] |
| - | [[Category: Gazanion, E | + | [[Category: Gazanion, E]] |
| - | [[Category: Guichou, J F | + | [[Category: Guichou, J F]] |
| - | [[Category: Labesse, G | + | [[Category: Labesse, G]] |
| - | [[Category: Sereno, D | + | [[Category: Sereno, D]] |
| - | [[Category: Vergnes, B | + | [[Category: Vergnes, B]] |
[[Category: Alpha/beta-hydrolase-like]] | [[Category: Alpha/beta-hydrolase-like]] | ||
[[Category: Cytoplasmic]] | [[Category: Cytoplasmic]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| - | [[Category: Nicotinamidase]] | ||
Revision as of 22:37, 3 January 2015
Crystal Structure of PnC1 from L. infantum in complex with nicotinate
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