3e7f

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3e7f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E7F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3E7F FirstGlance]. <br>
<table><tr><td colspan='2'>[[3e7f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E7F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3E7F FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6PG:6-PHOSPHOGLUCONIC+ACID'>6PG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6PG:6-PHOSPHOGLUCONIC+ACID'>6PG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2j0e|2j0e]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2j0e|2j0e]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">6pgl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5691 Trypanosoma brucei])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">6pgl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5691 Trypanosoma brucei])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gluconolactonase Gluconolactonase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.17 3.1.1.17] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gluconolactonase Gluconolactonase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.17 3.1.1.17] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e7f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3e7f RCSB], [http://www.ebi.ac.uk/pdbsum/3e7f PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e7f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3e7f RCSB], [http://www.ebi.ac.uk/pdbsum/3e7f PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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Insights into the enzymatic mechanism of 6-phosphogluconolactonase from Trypanosoma brucei using structural data and molecular dynamics simulation.,Duclert-Savatier N, Poggi L, Miclet E, Lopes P, Ouazzani J, Chevalier N, Nilges M, Delarue M, Stoven V J Mol Biol. 2009 May 22;388(5):1009-21. Epub 2009 Apr 1. PMID:19345229<ref>PMID:19345229</ref>
Insights into the enzymatic mechanism of 6-phosphogluconolactonase from Trypanosoma brucei using structural data and molecular dynamics simulation.,Duclert-Savatier N, Poggi L, Miclet E, Lopes P, Ouazzani J, Chevalier N, Nilges M, Delarue M, Stoven V J Mol Biol. 2009 May 22;388(5):1009-21. Epub 2009 Apr 1. PMID:19345229<ref>PMID:19345229</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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[[Category: Gluconolactonase]]
[[Category: Gluconolactonase]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
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[[Category: Delarue, M.]]
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[[Category: Delarue, M]]
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[[Category: Duclert-Savatier, N.]]
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[[Category: Duclert-Savatier, N]]
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[[Category: Poggi, L.]]
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[[Category: Poggi, L]]
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[[Category: Stoven, V.]]
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[[Category: Stoven, V]]
[[Category: 6-phosphogluconolactonase]]
[[Category: 6-phosphogluconolactonase]]
[[Category: Catalytic mechanism]]
[[Category: Catalytic mechanism]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Pentose phosphate pathway]]
[[Category: Pentose phosphate pathway]]
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[[Category: Trypanosoma brucei]]
 
[[Category: Zinc binding site]]
[[Category: Zinc binding site]]

Revision as of 22:44, 3 January 2015

Crystal structure of 6-phosphogluconolactonase from Trypanosoma brucei complexed with 6-phosphogluconic acid

3e7f, resolution 2.20Å

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