2ltm
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ltm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LTM FirstGlance]. <br> | <table><tr><td colspan='2'>[[2ltm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LTM FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CGI-33, HIRIP5, NFU1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CGI-33, HIRIP5, NFU1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ltm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ltm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ltm RCSB], [http://www.ebi.ac.uk/pdbsum/2ltm PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ltm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ltm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ltm RCSB], [http://www.ebi.ac.uk/pdbsum/2ltm PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/NFU1_HUMAN NFU1_HUMAN]] Fatal multiple mitochondrial dysfunction syndrome;Fatal infantile encephalopathy-pulmonary hypertension syndrome. Multiple mitochondrial dysfunctions syndrome 1 (MMDS1) [MIM:[http://omim.org/entry/605711 605711]]: A severe disorder of systemic energy metabolism, resulting in weakness, respiratory failure, lack of neurologic development, lactic acidosis, hyperglycinemia and early death. Some patients show failure to thrive, pulmonary hypertension, hypotonia and irritability. Biochemical features include severe combined deficiency of the 2-oxoacid dehydrogenases, defective lipoic acid synthesis and reduction in activity of mitochondrial respiratory chain complexes. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:21944046</ref> <ref>PMID:22077971</ref> | [[http://www.uniprot.org/uniprot/NFU1_HUMAN NFU1_HUMAN]] Fatal multiple mitochondrial dysfunction syndrome;Fatal infantile encephalopathy-pulmonary hypertension syndrome. Multiple mitochondrial dysfunctions syndrome 1 (MMDS1) [MIM:[http://omim.org/entry/605711 605711]]: A severe disorder of systemic energy metabolism, resulting in weakness, respiratory failure, lack of neurologic development, lactic acidosis, hyperglycinemia and early death. Some patients show failure to thrive, pulmonary hypertension, hypotonia and irritability. Biochemical features include severe combined deficiency of the 2-oxoacid dehydrogenases, defective lipoic acid synthesis and reduction in activity of mitochondrial respiratory chain complexes. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:21944046</ref> <ref>PMID:22077971</ref> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Acton, T B | + | [[Category: Acton, T B]] |
| - | [[Category: Everett, J K | + | [[Category: Everett, J K]] |
| - | [[Category: Hamilton, K | + | [[Category: Hamilton, K]] |
| - | [[Category: Huang, Y J | + | [[Category: Huang, Y J]] |
| - | [[Category: Janjua, H | + | [[Category: Janjua, H]] |
| - | [[Category: Kohan, E | + | [[Category: Kohan, E]] |
| - | [[Category: Lee, H | + | [[Category: Lee, H]] |
| - | [[Category: Liu, G | + | [[Category: Liu, G]] |
| - | [[Category: MPP, Mitochondrial Protein Partnership | + | [[Category: MPP, Mitochondrial Protein Partnership]] |
| - | [[Category: Montelione, G T | + | [[Category: Montelione, G T]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Shastry, R | + | [[Category: Shastry, R]] |
| - | [[Category: Xiao, R | + | [[Category: Xiao, R]] |
[[Category: Electron transport]] | [[Category: Electron transport]] | ||
[[Category: Mitochondrial protein partnership]] | [[Category: Mitochondrial protein partnership]] | ||
[[Category: Mpp]] | [[Category: Mpp]] | ||
[[Category: Nesg]] | [[Category: Nesg]] | ||
| - | [[Category: | + | [[Category: PSI, Protein structure initiative]] |
| - | + | ||
[[Category: Psi-biology]] | [[Category: Psi-biology]] | ||
| - | [[Category: Structural genomic]] | ||
Revision as of 22:45, 3 January 2015
Solution NMR Structure of NFU1 Iron-Sulfur Cluster Scaffold Homolog from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR2876B
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Categories: Homo sapiens | Acton, T B | Everett, J K | Hamilton, K | Huang, Y J | Janjua, H | Kohan, E | Lee, H | Liu, G | MPP, Mitochondrial Protein Partnership | Montelione, G T | Structural genomic | Shastry, R | Xiao, R | Electron transport | Mitochondrial protein partnership | Mpp | Nesg | PSI, Protein structure initiative | Psi-biology
