2yl8
From Proteopedia
(Difference between revisions)
| Line 2: | Line 2: | ||
<StructureSection load='2yl8' size='340' side='right' caption='[[2yl8]], [[Resolution|resolution]] 1.75Å' scene=''> | <StructureSection load='2yl8' size='340' side='right' caption='[[2yl8]], [[Resolution|resolution]] 1.75Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2yl8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YL8 OCA]. <br> | + | <table><tr><td colspan='2'>[[2yl8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YL8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YL8 FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yl9|2yl9]], [[2yla|2yla]], [[2yl6|2yl6]], [[2yl5|2yl5]], [[2yll|2yll]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yl9|2yl9]], [[2yla|2yla]], [[2yl6|2yl6]], [[2yl5|2yl5]], [[2yll|2yll]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yl8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yl8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yl8 RCSB], [http://www.ebi.ac.uk/pdbsum/2yl8 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yl8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yl8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yl8 RCSB], [http://www.ebi.ac.uk/pdbsum/2yl8 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 14: | Line 14: | ||
Inhibition of the Pneumococcal Virulence Factor StrH and Molecular Insights into N-Glycan Recognition and Hydrolysis.,Pluvinage B, Higgins MA, Abbott DW, Robb C, Dalia AB, Deng L, Weiser JN, Parsons TB, Fairbanks AJ, Vocadlo DJ, Boraston AB Structure. 2011 Nov 9;19(11):1603-14. PMID:22078560<ref>PMID:22078560</ref> | Inhibition of the Pneumococcal Virulence Factor StrH and Molecular Insights into N-Glycan Recognition and Hydrolysis.,Pluvinage B, Higgins MA, Abbott DW, Robb C, Dalia AB, Deng L, Weiser JN, Parsons TB, Fairbanks AJ, Vocadlo DJ, Boraston AB Structure. 2011 Nov 9;19(11):1603-14. PMID:22078560<ref>PMID:22078560</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Beta-Hexosaminidase|Beta-Hexosaminidase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 22: | Line 25: | ||
[[Category: Beta-N-acetylhexosaminidase]] | [[Category: Beta-N-acetylhexosaminidase]] | ||
[[Category: Streptococcus pneumoniae]] | [[Category: Streptococcus pneumoniae]] | ||
| - | [[Category: Abbott, D W | + | [[Category: Abbott, D W]] |
| - | [[Category: Boraston, A B | + | [[Category: Boraston, A B]] |
| - | [[Category: Dalia, A B | + | [[Category: Dalia, A B]] |
| - | [[Category: Deng, L | + | [[Category: Deng, L]] |
| - | [[Category: Fairbanks, A J | + | [[Category: Fairbanks, A J]] |
| - | [[Category: Higgins, M A | + | [[Category: Higgins, M A]] |
| - | [[Category: Parsons, T B | + | [[Category: Parsons, T B]] |
| - | [[Category: Pluvinage, B | + | [[Category: Pluvinage, B]] |
| - | [[Category: Robb, C | + | [[Category: Robb, C]] |
| - | [[Category: Vocadlo, D J | + | [[Category: Vocadlo, D J]] |
| - | [[Category: Weiser, J N | + | [[Category: Weiser, J N]] |
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 22:47, 3 January 2015
INHIBITION OF THE PNEUMOCOCCAL VIRULENCE FACTOR STRH AND MOLECULAR INSIGHTS INTO N-GLYCAN RECOGNITION AND HYDROLYSIS
| |||||||||||
