2xni
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2xni]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XNI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XNI FirstGlance]. <br> | <table><tr><td colspan='2'>[[2xni]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XNI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XNI FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TR8:(1-{[(10-TERT-BUTYL-15,15-DIMETHYL-3,9,12-TRIOXO-6,7,9,10,11,12,14,15,16,17,18,19,23,23A-TETRADECAHYDRO-1H,5H-2,23 5,8-DIMETHANO-4,13,2,8,11-BENZODIOXATRIAZACYCLOHENICOSIN-7(3H)-YL)CARBONYL]AMINO}-3-HYDROXYPROPYL)(TRIHYDROXY)BORATE(1-)'>TR8</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TR8:(1-{[(10-TERT-BUTYL-15,15-DIMETHYL-3,9,12-TRIOXO-6,7,9,10,11,12,14,15,16,17,18,19,23,23A-TETRADECAHYDRO-1H,5H-2,23 5,8-DIMETHANO-4,13,2,8,11-BENZODIOXATRIAZACYCLOHENICOSIN-7(3H)-YL)CARBONYL]AMINO}-3-HYDROXYPROPYL)(TRIHYDROXY)BORATE(1-)'>TR8</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xcf|2xcf]], [[2xcn|2xcn]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xcf|2xcf]], [[2xcn|2xcn]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xni OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xni RCSB], [http://www.ebi.ac.uk/pdbsum/2xni PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xni OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xni RCSB], [http://www.ebi.ac.uk/pdbsum/2xni PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Hepatitis c virus]] | [[Category: Hepatitis c virus]] | ||
| - | [[Category: Baker, S J | + | [[Category: Baker, S J]] |
| - | [[Category: Carballo, L H | + | [[Category: Carballo, L H]] |
| - | [[Category: Convery, M A | + | [[Category: Convery, M A]] |
| - | [[Category: Creech, K L | + | [[Category: Creech, K L]] |
| - | [[Category: Crosby, R M | + | [[Category: Crosby, R M]] |
| - | [[Category: Ding, C Z | + | [[Category: Ding, C Z]] |
| - | [[Category: Fan, D | + | [[Category: Fan, D]] |
| - | [[Category: Grimes, R M | + | [[Category: Grimes, R M]] |
| - | [[Category: Hubbard, J A | + | [[Category: Hubbard, J A]] |
| - | [[Category: Jarvest, R L | + | [[Category: Jarvest, R L]] |
| - | [[Category: Kazmierski, W M | + | [[Category: Kazmierski, W M]] |
| - | [[Category: Li, Q | + | [[Category: Li, Q]] |
| - | [[Category: Li, X | + | [[Category: Li, X]] |
| - | [[Category: Liao, L | + | [[Category: Liao, L]] |
| - | [[Category: Liu, Y | + | [[Category: Liu, Y]] |
| - | [[Category: Mcdowell, W | + | [[Category: Mcdowell, W]] |
| - | [[Category: Nassau, P M | + | [[Category: Nassau, P M]] |
| - | [[Category: Ni, Z J | + | [[Category: Ni, Z J]] |
| - | [[Category: Pennicott, L E | + | [[Category: Pennicott, L E]] |
| - | [[Category: Plattner, J J | + | [[Category: Plattner, J J]] |
| - | [[Category: Qian, X | + | [[Category: Qian, X]] |
| - | [[Category: Skarzynski, T J | + | [[Category: Skarzynski, T J]] |
| - | [[Category: Slater, M J | + | [[Category: Slater, M J]] |
| - | [[Category: Smith, G K | + | [[Category: Smith, G K]] |
| - | [[Category: Thommes, P | + | [[Category: Thommes, P]] |
| - | [[Category: Wright, J | + | [[Category: Wright, J]] |
| - | [[Category: Wright, L L | + | [[Category: Wright, L L]] |
| - | [[Category: Zhang, S | + | [[Category: Zhang, S]] |
| - | [[Category: Zhang, Y K | + | [[Category: Zhang, Y K]] |
| - | [[Category: Zhou, Y | + | [[Category: Zhou, Y]] |
| - | [[Category: Zou, W | + | [[Category: Zou, W]] |
[[Category: Hydrolase-hydrolase regulator complex]] | [[Category: Hydrolase-hydrolase regulator complex]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
Revision as of 22:51, 3 January 2015
Protein-ligand complex of a novel macrocyclic HCV NS3 protease inhibitor derived from amino cyclic boronates
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Categories: Hepatitis c virus | Baker, S J | Carballo, L H | Convery, M A | Creech, K L | Crosby, R M | Ding, C Z | Fan, D | Grimes, R M | Hubbard, J A | Jarvest, R L | Kazmierski, W M | Li, Q | Li, X | Liao, L | Liu, Y | Mcdowell, W | Nassau, P M | Ni, Z J | Pennicott, L E | Plattner, J J | Qian, X | Skarzynski, T J | Slater, M J | Smith, G K | Thommes, P | Wright, J | Wright, L L | Zhang, S | Zhang, Y K | Zhou, Y | Zou, W | Hydrolase-hydrolase regulator complex | Serine protease
