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2ge9

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[[Image:2ge9.gif|left|200px]]<br /><applet load="2ge9" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2ge9.gif|left|200px]]
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caption="2ge9" />
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'''Solution Structures of the SH2 domain of Bruton's Tyrosine Kinase'''<br />
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{{Structure
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|PDB= 2ge9 |SIZE=350|CAPTION= <scene name='initialview01'>2ge9</scene>
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|SITE=
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|LIGAND=
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|ACTIVITY= [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2]
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|GENE= BTK, AGMX1, ATK, BPK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Solution Structures of the SH2 domain of Bruton's Tyrosine Kinase'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2GE9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Active as [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GE9 OCA].
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2GE9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GE9 OCA].
==Reference==
==Reference==
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Solution structure and phosphopeptide binding of the SH2 domain from the human Bruton's tyrosine kinase., Huang KC, Cheng HT, Pai MT, Tzeng SR, Cheng JW, J Biomol NMR. 2006 Sep;36(1):73-8. Epub 2006 Sep 13. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16969585 16969585]
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Solution structure and phosphopeptide binding of the SH2 domain from the human Bruton's tyrosine kinase., Huang KC, Cheng HT, Pai MT, Tzeng SR, Cheng JW, J Biomol NMR. 2006 Sep;36(1):73-8. Epub 2006 Sep 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16969585 16969585]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: structure]]
[[Category: structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:30:59 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:03:40 2008''

Revision as of 15:03, 20 March 2008

Image:2ge9.gif


PDB ID 2ge9

Drag the structure with the mouse to rotate
Gene: BTK, AGMX1, ATK, BPK (Homo sapiens)
Activity: Transferase, with EC number and 2.7.10.2 2.7.10.1 and 2.7.10.2
Coordinates: save as pdb, mmCIF, xml



Solution Structures of the SH2 domain of Bruton's Tyrosine Kinase


Disease

Known diseases associated with this structure: Agammaglobulinemia, type 1, X-linked OMIM:[300300], XLA and isolated growth hormone deficiency OMIM:[300300]

About this Structure

2GE9 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Solution structure and phosphopeptide binding of the SH2 domain from the human Bruton's tyrosine kinase., Huang KC, Cheng HT, Pai MT, Tzeng SR, Cheng JW, J Biomol NMR. 2006 Sep;36(1):73-8. Epub 2006 Sep 13. PMID:16969585

Page seeded by OCA on Thu Mar 20 17:03:40 2008

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