2gej
From Proteopedia
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| - | [[Image:2gej.jpg|left|200px]] | + | [[Image:2gej.jpg|left|200px]] |
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| - | '''Crystal Structure of phosphatidylinositol mannosyltransferase (PimA) from Mycobacterium smegmatis in complex with GDP-Man''' | + | {{Structure |
| + | |PDB= 2gej |SIZE=350|CAPTION= <scene name='initialview01'>2gej</scene>, resolution 2.600Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=GDD:GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE'>GDD</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= PIMA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1772 Mycobacterium smegmatis]) | ||
| + | }} | ||
| + | |||
| + | '''Crystal Structure of phosphatidylinositol mannosyltransferase (PimA) from Mycobacterium smegmatis in complex with GDP-Man''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2GEJ is a [ | + | 2GEJ is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GEJ OCA]. |
==Reference== | ==Reference== | ||
| - | Crystallization and preliminary crystallographic analysis of PimA, an essential mannosyltransferase from Mycobacterium smegmatis., Guerin ME, Buschiazzo A, Kordulakova J, Jackson M, Alzari PM, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 May 1;61(Pt, 5):518-20. Epub 2005 Apr 22. PMID:[http:// | + | Crystallization and preliminary crystallographic analysis of PimA, an essential mannosyltransferase from Mycobacterium smegmatis., Guerin ME, Buschiazzo A, Kordulakova J, Jackson M, Alzari PM, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 May 1;61(Pt, 5):518-20. Epub 2005 Apr 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16511084 16511084] |
[[Category: Mycobacterium smegmatis]] | [[Category: Mycobacterium smegmatis]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
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[[Category: rossmann fold]] | [[Category: rossmann fold]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:03:44 2008'' |
Revision as of 15:03, 20 March 2008
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| , resolution 2.600Å | |||||||
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| Ligands: | |||||||
| Gene: | PIMA (Mycobacterium smegmatis) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal Structure of phosphatidylinositol mannosyltransferase (PimA) from Mycobacterium smegmatis in complex with GDP-Man
Overview
Phosphatidylinositol mannosyltransferase (PimA) is an essential enzyme for mycobacterial growth that catalyses the first mannosylation step in phosphatidyl-myo-inositol mannoside (PIM) biosynthesis. The enzyme belongs to the large GT4 family of glycosyltransferases, for which no structure is currently available. Recombinant purified PimA from Mycobacterium smegmatis has been crystallized in the presence of GDP and myo-inositol. The crystals belong to space group P2(1)2(1)2(1), with unit-cell parameters a = 37.2, b = 72.4, c = 138.2 A, and diffract to 2.4 A resolution.
About this Structure
2GEJ is a Protein complex structure of sequences from Mycobacterium smegmatis. Full crystallographic information is available from OCA.
Reference
Crystallization and preliminary crystallographic analysis of PimA, an essential mannosyltransferase from Mycobacterium smegmatis., Guerin ME, Buschiazzo A, Kordulakova J, Jackson M, Alzari PM, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 May 1;61(Pt, 5):518-20. Epub 2005 Apr 22. PMID:16511084
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