2y7j

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<StructureSection load='2y7j' size='340' side='right' caption='[[2y7j]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2y7j' size='340' side='right' caption='[[2y7j]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2y7j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7J OCA]. <br>
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<table><tr><td colspan='2'>[[2y7j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y7J FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B49:N-[2-(DIETHYLAMINO)ETHYL]-5-[(Z)-(5-FLUORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE'>B49</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B49:N-[2-(DIETHYLAMINO)ETHYL]-5-[(Z)-(5-FLUORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE'>B49</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphorylase_kinase Phosphorylase kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.19 2.7.11.19] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y7j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y7j RCSB], [http://www.ebi.ac.uk/pdbsum/2y7j PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y7j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y7j RCSB], [http://www.ebi.ac.uk/pdbsum/2y7j PDBsum]</span></td></tr>
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<table>
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</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/PHKG2_HUMAN PHKG2_HUMAN]] Glycogen storage disease due to liver phosphorylase kinase deficiency. The disease is caused by mutations affecting the gene represented in this entry.
[[http://www.uniprot.org/uniprot/PHKG2_HUMAN PHKG2_HUMAN]] Glycogen storage disease due to liver phosphorylase kinase deficiency. The disease is caused by mutations affecting the gene represented in this entry.
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phosphorylase kinase]]
[[Category: Phosphorylase kinase]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith, C H]]
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[[Category: Berridge, G.]]
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[[Category: Berridge, G]]
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[[Category: Bountra, C.]]
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[[Category: Bountra, C]]
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[[Category: Brenner, B.]]
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[[Category: Brenner, B]]
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[[Category: Burgess-Brown, N.]]
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[[Category: Burgess-Brown, N]]
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[[Category: Che, K H.]]
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[[Category: Che, K H]]
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[[Category: Delft, F Von.]]
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[[Category: Delft, F Von]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards, A M]]
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[[Category: Elkins, J M.]]
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[[Category: Elkins, J M]]
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[[Category: Fedorov, O.]]
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[[Category: Fedorov, O]]
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[[Category: Knapp, S.]]
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[[Category: Knapp, S]]
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[[Category: Krojer, T.]]
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[[Category: Krojer, T]]
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[[Category: Muniz, J R.C.]]
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[[Category: Muniz, J R.C]]
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[[Category: Rellos, P.]]
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[[Category: Rellos, P]]
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[[Category: Savitsky, P.]]
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[[Category: Savitsky, P]]
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[[Category: Shrestha, A.]]
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[[Category: Shrestha, A]]
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[[Category: Vollmar, M.]]
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[[Category: Vollmar, M]]
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[[Category: Wang, J.]]
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[[Category: Wang, J]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt, J]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 23:13, 3 January 2015

STRUCTURE OF HUMAN PHOSPHORYLASE KINASE, GAMMA 2

2y7j, resolution 2.50Å

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