2x9p
From Proteopedia
(Difference between revisions)
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<StructureSection load='2x9p' size='340' side='right' caption='[[2x9p]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='2x9p' size='340' side='right' caption='[[2x9p]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2x9p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_natalensis Streptomyces natalensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X9P OCA]. <br> | + | <table><tr><td colspan='2'>[[2x9p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_natalensis Streptomyces natalensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X9P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X9P FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xbk|2xbk]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xbk|2xbk]]</td></tr> |
| - | <tr | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x9p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x9p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x9p RCSB], [http://www.ebi.ac.uk/pdbsum/2x9p PDBsum]</span></td></tr> |
| - | + | </table> | |
| - | <table> | + | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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Structure of cytochrome P450 PimD suggests epoxidation of the polyene macrolide pimaricin occurs via a hydroperoxoferric intermediate.,Kells PM, Ouellet H, Santos-Aberturas J, Aparicio JF, Podust LM Chem Biol. 2010 Aug 27;17(8):841-51. PMID:20797613<ref>PMID:20797613</ref> | Structure of cytochrome P450 PimD suggests epoxidation of the polyene macrolide pimaricin occurs via a hydroperoxoferric intermediate.,Kells PM, Ouellet H, Santos-Aberturas J, Aparicio JF, Podust LM Chem Biol. 2010 Aug 27;17(8):841-51. PMID:20797613<ref>PMID:20797613</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Streptomyces natalensis]] | [[Category: Streptomyces natalensis]] | ||
| - | [[Category: Aparicio, J F | + | [[Category: Aparicio, J F]] |
| - | [[Category: Kells, P M | + | [[Category: Kells, P M]] |
| - | [[Category: Ouellet, H | + | [[Category: Ouellet, H]] |
| - | [[Category: Podust, L M | + | [[Category: Podust, L M]] |
| - | [[Category: Santos-Aberturas, J | + | [[Category: Santos-Aberturas, J]] |
[[Category: Epoxidation]] | [[Category: Epoxidation]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
Revision as of 23:18, 3 January 2015
X-RAY STRUCTURE OF THE SUBSTRATE-FREE CYTOCHROME P450 PIMD -A POLYENE MACROLIDE ANTIBIOTIC PIMARICIN EPOXIDASE
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