3pdm
From Proteopedia
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| - | + | ==Hibiscus Latent Singapore virus== | |
| - | ===Hibiscus | + | <StructureSection load='3pdm' size='340' side='right' caption='[[3pdm]], [[Resolution|resolution]] 3.50Å' scene=''> |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[3pdm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hibiscus_latent_singapore_virus Hibiscus latent singapore virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PDM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PDM FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pdm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pdm RCSB], [http://www.ebi.ac.uk/pdbsum/3pdm PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Hibiscus latent Singapore virus (HLSV) is a rigid rod-shaped plant virus and a new member of the Tobamovirus family. Unlike all other Tobamoviruses, the HLSV genome contains a unique poly(A) tract in its 3' untranslated region. The virion is composed of a monomeric coat protein (CP) unit of 18 kDa, arranged as a right-handed helix around the virus axis. We have determined the structure of HLSV at 3.5 A by X-ray fiber diffraction and refined it to an R-factor of 0.096. While the overall structure of the HLSV CP resembles that of other Tobamoviruses, there are a few unique differences. There is a kink in the LR helix due to the presence of His122. Also, the adjacent Lys123 may further destabilize the helix by positive charge repulsion, making the kink more pronounced. The His122-Asp88 salt bridge provides significant stability to the loop adjacent to the RR helix. Carboxyl-carboxylate interactions that drive viral disassembly are also different in HLSV. The nucleotide recognition mechanisms for virus assembly between HLSV and ribgrass mosaic virus are similar, but different between tobacco mosaic virus and cucumber green mottle mosaic virus. | ||
| - | + | Structure of Hibiscus Latent Singapore Virus by Fiber Diffraction: A Nonconserved His122 Contributes to Coat Protein Stability.,Tewary SK, Oda T, Kendall A, Bian W, Stubbs G, Wong SM, Swaminathan K J Mol Biol. 2010 Dec 30. PMID:21195089<ref>PMID:21195089</ref> | |
| - | + | ||
| - | == | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
| - | + | </div> | |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Hibiscus latent singapore virus]] | [[Category: Hibiscus latent singapore virus]] | ||
| - | [[Category: Swaminathan, K | + | [[Category: Swaminathan, K]] |
| - | [[Category: Tewary, S K | + | [[Category: Tewary, S K]] |
| - | [[Category: Wong, S M | + | [[Category: Wong, S M]] |
[[Category: Helical virus]] | [[Category: Helical virus]] | ||
[[Category: Virus]] | [[Category: Virus]] | ||
[[Category: Virus-rna complex]] | [[Category: Virus-rna complex]] | ||
Revision as of 23:19, 3 January 2015
Hibiscus Latent Singapore virus
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