2ydu
From Proteopedia
(Difference between revisions)
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<StructureSection load='2ydu' size='340' side='right' caption='[[2ydu]], [[Resolution|resolution]] 1.79Å' scene=''> | <StructureSection load='2ydu' size='340' side='right' caption='[[2ydu]], [[Resolution|resolution]] 1.79Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2ydu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YDU OCA]. <br> | + | <table><tr><td colspan='2'>[[2ydu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YDU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YDU FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=79W:3-[(2S)-1,1-DIOXIDO-4-OXOTETRAHYDROTHIOPHEN-2-YL]BENZALDEHYDE'>79W</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=79W:3-[(2S)-1,1-DIOXIDO-4-OXOTETRAHYDROTHIOPHEN-2-YL]BENZALDEHYDE'>79W</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1qz0|1qz0]], [[2y2f|2y2f]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1qz0|1qz0]], [[2y2f|2y2f]]</td></tr> |
| - | <tr | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ydu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ydu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ydu RCSB], [http://www.ebi.ac.uk/pdbsum/2ydu PDBsum]</span></td></tr> |
| - | + | </table> | |
| - | <table> | + | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Isothiazolidinone (IZD) as a phosphoryl mimetic in inhibitors of the Yersinia pestis protein tyrosine phosphatase YopH.,Kim SE, Bahta M, Lountos GT, Ulrich RG, Burke TR Jr, Waugh DS Acta Crystallogr D Biol Crystallogr. 2011 Jul;67(Pt 7):639-45. doi:, 10.1107/S0907444911018610. Epub 2011 Jun 11. PMID:21697602<ref>PMID:21697602</ref> | Isothiazolidinone (IZD) as a phosphoryl mimetic in inhibitors of the Yersinia pestis protein tyrosine phosphatase YopH.,Kim SE, Bahta M, Lountos GT, Ulrich RG, Burke TR Jr, Waugh DS Acta Crystallogr D Biol Crystallogr. 2011 Jul;67(Pt 7):639-45. doi:, 10.1107/S0907444911018610. Epub 2011 Jun 11. PMID:21697602<ref>PMID:21697602</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Yersinia pestis]] | [[Category: Yersinia pestis]] | ||
| - | [[Category: Bahta, M | + | [[Category: Bahta, M]] |
| - | [[Category: Burke, T R | + | [[Category: Burke, T R]] |
| - | [[Category: Kim, S E | + | [[Category: Kim, S E]] |
| - | [[Category: Lountos, G T | + | [[Category: Lountos, G T]] |
| - | [[Category: Ulrich, R G | + | [[Category: Ulrich, R G]] |
| - | [[Category: Waugh, D S | + | [[Category: Waugh, D S]] |
[[Category: Antiplague drug design]] | [[Category: Antiplague drug design]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 23:22, 3 January 2015
CRYSTAL STRUCTURE OF YOPH IN COMPLEX WITH 3-(1,1-DIOXIDO-3-OXOISOTHIAZOLIDIN-5-YL)BENZALDEYDE
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