2wbu

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<StructureSection load='2wbu' size='340' side='right' caption='[[2wbu]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2wbu' size='340' side='right' caption='[[2wbu]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2wbu]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBU OCA]. <br>
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<table><tr><td colspan='2'>[[2wbu]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WBU FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wbs|2wbs]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wbs|2wbs]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wbu RCSB], [http://www.ebi.ac.uk/pdbsum/2wbu PDBsum]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wbu RCSB], [http://www.ebi.ac.uk/pdbsum/2wbu PDBsum]</span></td></tr>
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</table>
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<table>
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== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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The structure of the Klf4 DNA-binding domain links to self-renewal and macrophage differentiation.,Schuetz A, Nana D, Rose C, Zocher G, Milanovic M, Koenigsmann J, Blasig R, Heinemann U, Carstanjen D Cell Mol Life Sci. 2011 Sep;68(18):3121-31. Epub 2011 Feb 3. PMID:21290164<ref>PMID:21290164</ref>
The structure of the Klf4 DNA-binding domain links to self-renewal and macrophage differentiation.,Schuetz A, Nana D, Rose C, Zocher G, Milanovic M, Koenigsmann J, Blasig R, Heinemann U, Carstanjen D Cell Mol Life Sci. 2011 Sep;68(18):3121-31. Epub 2011 Feb 3. PMID:21290164<ref>PMID:21290164</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Carstanjen, D.]]
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[[Category: Carstanjen, D]]
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[[Category: Heinemann, U.]]
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[[Category: Heinemann, U]]
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[[Category: Schuetz, A.]]
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[[Category: Schuetz, A]]
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[[Category: Zocher, G.]]
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[[Category: Zocher, G]]
[[Category: Activator]]
[[Category: Activator]]
[[Category: Dna-binding]]
[[Category: Dna-binding]]

Revision as of 23:25, 3 January 2015

CRYSTAL STRUCTURE OF THE ZINC FINGER DOMAIN OF KLF4 BOUND TO ITS TARGET DNA

2wbu, resolution 2.50Å

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