3vgj
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3vgj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VGJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VGJ FirstGlance]. <br> | <table><tr><td colspan='2'>[[3vgj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VGJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VGJ FirstGlance]. <br> | ||
- | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=YAP:5-O-[(R)-{[(2S)-2-AMINO-3-(4-HYDROXYPHENYL)PROPANOYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE'>YAP</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=YAP:5-O-[(R)-{[(2S)-2-AMINO-3-(4-HYDROXYPHENYL)PROPANOYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE'>YAP</scene></td></tr> |
- | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1q11|1q11]], [[1n3l|1n3l]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1q11|1q11]], [[1n3l|1n3l]]</td></tr> |
- | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAL8P1.125 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 Plasmodium falciparum])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAL8P1.125 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 Plasmodium falciparum])</td></tr> |
- | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tyrosine--tRNA_ligase Tyrosine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.1 6.1.1.1] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tyrosine--tRNA_ligase Tyrosine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.1 6.1.1.1] </span></td></tr> |
- | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vgj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vgj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vgj RCSB], [http://www.ebi.ac.uk/pdbsum/3vgj PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vgj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vgj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vgj RCSB], [http://www.ebi.ac.uk/pdbsum/3vgj PDBsum]</span></td></tr> |
- | <table> | + | </table> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Malaria parasite tyrosyl-tRNA synthetase secretion triggers pro-inflammatory responses.,Bhatt TK, Khan S, Dwivedi VP, Banday MM, Sharma A, Chandele A, Camacho N, de Pouplana LR, Wu Y, Craig AG, Mikkonen AT, Maier AG, Yogavel M, Sharma A Nat Commun. 2011 Nov 8;2:530. doi: 10.1038/ncomms1522. PMID:22068597<ref>PMID:22068597</ref> | Malaria parasite tyrosyl-tRNA synthetase secretion triggers pro-inflammatory responses.,Bhatt TK, Khan S, Dwivedi VP, Banday MM, Sharma A, Chandele A, Camacho N, de Pouplana LR, Wu Y, Craig AG, Mikkonen AT, Maier AG, Yogavel M, Sharma A Nat Commun. 2011 Nov 8;2:530. doi: 10.1038/ncomms1522. PMID:22068597<ref>PMID:22068597</ref> | ||
- | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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[[Category: Plasmodium falciparum]] | [[Category: Plasmodium falciparum]] | ||
[[Category: Tyrosine--tRNA ligase]] | [[Category: Tyrosine--tRNA ligase]] | ||
- | [[Category: Banday, M M | + | [[Category: Banday, M M]] |
- | [[Category: Bhatt, T K | + | [[Category: Bhatt, T K]] |
- | [[Category: Khan, S | + | [[Category: Khan, S]] |
- | [[Category: Sharma, A | + | [[Category: Sharma, A]] |
- | [[Category: Yogavel, M | + | [[Category: Yogavel, M]] |
[[Category: Ligase]] | [[Category: Ligase]] | ||
[[Category: Synthetase]] | [[Category: Synthetase]] | ||
[[Category: Tyrr]] | [[Category: Tyrr]] |
Revision as of 09:19, 4 January 2015
Crystal of Plasmodium falciparum tyrosyl-tRNA synthetase (PfTyrRS)in complex with adenylate analog
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