3ufa
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3ufa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staa8 Staa8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UFA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UFA FirstGlance]. <br> | <table><tr><td colspan='2'>[[3ufa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staa8 Staa8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UFA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UFA FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=VPF:N-(3-CARBOXYPROPANOYL)-L-VALYL-N-[(1S)-2-PHENYL-1-PHOSPHONOETHYL]-L-PROLINAMIDE'>VPF</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=VPF:N-(3-CARBOXYPROPANOYL)-L-VALYL-N-[(1S)-2-PHENYL-1-PHOSPHONOETHYL]-L-PROLINAMIDE'>VPF</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">splA, SAOUHSC_01942 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93061 STAA8])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">splA, SAOUHSC_01942 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93061 STAA8])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ufa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ufa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ufa RCSB], [http://www.ebi.ac.uk/pdbsum/3ufa PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ufa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ufa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ufa RCSB], [http://www.ebi.ac.uk/pdbsum/3ufa PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Development and binding characteristics of phosphonate inhibitors of SplA protease from Staphylococcus aureus.,Burchacka E, Zdzalik M, Niemczyk JS, Pustelny K, Popowicz G, Wladyka B, Dubin A, Potempa J, Sienczyk M, Dubin G, Oleksyszyn J Protein Sci. 2013 Dec 4. doi: 10.1002/pro.2403. PMID:24375505<ref>PMID:24375505</ref> | Development and binding characteristics of phosphonate inhibitors of SplA protease from Staphylococcus aureus.,Burchacka E, Zdzalik M, Niemczyk JS, Pustelny K, Popowicz G, Wladyka B, Dubin A, Potempa J, Sienczyk M, Dubin G, Oleksyszyn J Protein Sci. 2013 Dec 4. doi: 10.1002/pro.2403. PMID:24375505<ref>PMID:24375505</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Staa8]] | [[Category: Staa8]] | ||
| - | [[Category: Dubin, G | + | [[Category: Dubin, G]] |
| - | [[Category: Oleksyszyn, J | + | [[Category: Oleksyszyn, J]] |
| - | [[Category: Pietrusewicz, E | + | [[Category: Pietrusewicz, E]] |
| - | [[Category: Popowicz, G M | + | [[Category: Popowicz, G M]] |
| - | [[Category: Potempa, J | + | [[Category: Potempa, J]] |
| - | [[Category: Pustelny, K | + | [[Category: Pustelny, K]] |
| - | [[Category: Stec-Niemczyk, J | + | [[Category: Stec-Niemczyk, J]] |
| - | [[Category: Zdzalik, M | + | [[Category: Zdzalik, M]] |
[[Category: Chymotrypsin like fold]] | [[Category: Chymotrypsin like fold]] | ||
[[Category: Extracellular protease]] | [[Category: Extracellular protease]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
Revision as of 09:28, 4 January 2015
Crystal structure of the staphylococcal serine protease SplA in complex with a specific phosphonate inhibitor
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