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3sgs

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3sgs]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SGS FirstGlance]. <br>
<table><tr><td colspan='2'>[[3sgs]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SGS FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sgm|3sgm]], [[3sgn|3sgn]], [[3sgo|3sgo]], [[3sgp|3sgp]], [[3sgr|3sgr]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sgm|3sgm]], [[3sgn|3sgn]], [[3sgo|3sgo]], [[3sgp|3sgp]], [[3sgr|3sgr]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sgs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sgs RCSB], [http://www.ebi.ac.uk/pdbsum/3sgs PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sgs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sgs RCSB], [http://www.ebi.ac.uk/pdbsum/3sgs PDBsum]</span></td></tr>
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<table>
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</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/CRYAB_HUMAN CRYAB_HUMAN]] Posterior polar cataract;Alpha-crystallinopathy;Zonular cataract;Familial isolated dilated cardiomyopathy;Fatal infantile hypertonic myofibrillar myopathy. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
[[http://www.uniprot.org/uniprot/CRYAB_HUMAN CRYAB_HUMAN]] Posterior polar cataract;Alpha-crystallinopathy;Zonular cataract;Familial isolated dilated cardiomyopathy;Fatal infantile hypertonic myofibrillar myopathy. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
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Atomic view of a toxic amyloid small oligomer.,Laganowsky A, Liu C, Sawaya MR, Whitelegge JP, Park J, Zhao M, Pensalfini A, Soriaga AB, Landau M, Teng PK, Cascio D, Glabe C, Eisenberg D Science. 2012 Mar 9;335(6073):1228-31. PMID:22403391<ref>PMID:22403391</ref>
Atomic view of a toxic amyloid small oligomer.,Laganowsky A, Liu C, Sawaya MR, Whitelegge JP, Park J, Zhao M, Pensalfini A, Soriaga AB, Landau M, Teng PK, Cascio D, Glabe C, Eisenberg D Science. 2012 Mar 9;335(6073):1228-31. PMID:22403391<ref>PMID:22403391</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cascio, D.]]
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[[Category: Cascio, D]]
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[[Category: Eisenberg, D.]]
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[[Category: Eisenberg, D]]
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[[Category: Laganowsky, A.]]
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[[Category: Laganowsky, A]]
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[[Category: Sawaya, M R.]]
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[[Category: Sawaya, M R]]
[[Category: Amyloid]]
[[Category: Amyloid]]
[[Category: Amyloid fibril]]
[[Category: Amyloid fibril]]
[[Category: Protein fibril]]
[[Category: Protein fibril]]

Revision as of 10:13, 4 January 2015

Amyloid-related segment of alphaB-crystallin residues 95-100

3sgs, resolution 1.70Å

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