4a1g
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4a1g]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A1G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A1G FirstGlance]. <br> | <table><tr><td colspan='2'>[[4a1g]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A1G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A1G FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a1g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a1g RCSB], [http://www.ebi.ac.uk/pdbsum/4a1g PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a1g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a1g RCSB], [http://www.ebi.ac.uk/pdbsum/4a1g PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/CASC5_HUMAN CASC5_HUMAN]] Autosomal recessive primary microcephaly. A chromosomal aberration involving CASC5 is associated with acute myeloblastic leukemia (AML). Translocation t(11;15)(q23;q14) with KMT2A/MLL1. May give rise to a KMT2A/MLL1-CASC5 fusion protein. The disease is caused by mutations affecting the gene represented in this entry. | [[http://www.uniprot.org/uniprot/CASC5_HUMAN CASC5_HUMAN]] Autosomal recessive primary microcephaly. A chromosomal aberration involving CASC5 is associated with acute myeloblastic leukemia (AML). Translocation t(11;15)(q23;q14) with KMT2A/MLL1. May give rise to a KMT2A/MLL1-CASC5 fusion protein. The disease is caused by mutations affecting the gene represented in this entry. | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
| - | [[Category: Krenn, V | + | [[Category: Krenn, V]] |
| - | [[Category: Li, X | + | [[Category: Li, X]] |
| - | [[Category: Musacchio, A | + | [[Category: Musacchio, A]] |
| - | [[Category: Santaguida, S | + | [[Category: Santaguida, S]] |
| - | [[Category: Wehenkel, A | + | [[Category: Wehenkel, A]] |
[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
[[Category: Kmn network]] | [[Category: Kmn network]] | ||
Revision as of 10:53, 4 January 2015
The crystal structure of the human Bub1 TPR domain in complex with the KI motif of Knl1
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