4cc6
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4cc6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CC6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CC6 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4cc6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CC6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CC6 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=L5Y:2-{[2-(1H-PYRAZOLO[3,4-C]PYRIDIN-3-YL)-6-(TRIFLUOROMETHYL)PYRIDIN-4-YL]AMINO}ETHANOL'>L5Y</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=L5Y:2-{[2-(1H-PYRAZOLO[3,4-C]PYRIDIN-3-YL)-6-(TRIFLUOROMETHYL)PYRIDIN-4-YL]AMINO}ETHANOL'>L5Y</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cc5|4cc5]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cc5|4cc5]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_ligase_(NAD(+)) DNA ligase (NAD(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.2 6.5.1.2] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_ligase_(NAD(+)) DNA ligase (NAD(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.2 6.5.1.2] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cc6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cc6 RCSB], [http://www.ebi.ac.uk/pdbsum/4cc6 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cc6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cc6 RCSB], [http://www.ebi.ac.uk/pdbsum/4cc6 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Amin, N | + | [[Category: Amin, N]] |
| - | [[Category: Benowitz, A B | + | [[Category: Benowitz, A B]] |
| - | [[Category: Chiarparin, E | + | [[Category: Chiarparin, E]] |
| - | [[Category: Cui, H | + | [[Category: Cui, H]] |
| - | [[Category: Deng, X | + | [[Category: Deng, X]] |
| - | [[Category: Heightman, T D | + | [[Category: Heightman, T D]] |
| - | [[Category: Holmes, D J | + | [[Category: Holmes, D J]] |
| - | [[Category: Hopkins, A | + | [[Category: Hopkins, A]] |
| - | [[Category: Howard, S | + | [[Category: Howard, S]] |
| - | [[Category: Huang, J | + | [[Category: Huang, J]] |
| - | [[Category: Jin, Q | + | [[Category: Jin, Q]] |
| - | [[Category: Kreatsoulas, C | + | [[Category: Kreatsoulas, C]] |
| - | [[Category: Martin, A C.L | + | [[Category: Martin, A C.L]] |
| - | [[Category: Massey, F | + | [[Category: Massey, F]] |
| - | [[Category: McCloskey, L | + | [[Category: McCloskey, L]] |
| - | [[Category: Mortenson, P N | + | [[Category: Mortenson, P N]] |
| - | [[Category: Pathuri, P | + | [[Category: Pathuri, P]] |
| - | [[Category: Tisi, D | + | [[Category: Tisi, D]] |
| - | [[Category: Williams, P A | + | [[Category: Williams, P A]] |
[[Category: Antibiotic design]] | [[Category: Antibiotic design]] | ||
[[Category: Liga]] | [[Category: Liga]] | ||
[[Category: Ligase]] | [[Category: Ligase]] | ||
Revision as of 12:26, 4 January 2015
Fragment-Based Discovery of 6 Azaindazoles As Inhibitors of Bacterial DNA Ligase
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Categories: Amin, N | Benowitz, A B | Chiarparin, E | Cui, H | Deng, X | Heightman, T D | Holmes, D J | Hopkins, A | Howard, S | Huang, J | Jin, Q | Kreatsoulas, C | Martin, A C.L | Massey, F | McCloskey, L | Mortenson, P N | Pathuri, P | Tisi, D | Williams, P A | Antibiotic design | Liga | Ligase
