4h55

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[[Image:4h55.jpg|left|200px]]
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==Crystal structure of Canavalia brasiliensis seed lectin (ConBr) in complex with beta-d-ribofuranose==
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<StructureSection load='4h55' size='340' side='right' caption='[[4h55]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4h55]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_brasiliensis Canavalia brasiliensis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4dps 4dps]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H55 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H55 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BDR:BETA-D-RIBOFURANOSYL'>BDR</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4dps|4dps]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h55 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h55 RCSB], [http://www.ebi.ac.uk/pdbsum/4h55 PDBsum]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CONA_CANBR CONA_CANBR]] Glucose/D-mannose specific lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from hamster and rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 20 ug/ml.<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:8891754</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref>
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{{STRUCTURE_4h55| PDB=4h55 | SCENE= }}
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==See Also==
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*[[Concanavalin A|Concanavalin A]]
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===Crystal structure of Canavalia brasiliensis seed lectin (ConBr) in complex with beta-d-ribofuranose===
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== References ==
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<references/>
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4h55]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_brasiliensis Canavalia brasiliensis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4dps 4dps]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H55 OCA].
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[[Category: Canavalia brasiliensis]]
[[Category: Canavalia brasiliensis]]
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[[Category: Cavada, B S.]]
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[[Category: Cavada, B S]]
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[[Category: Delatorre, P.]]
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[[Category: Delatorre, P]]
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[[Category: Farias, D L.]]
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[[Category: Farias, D L]]
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[[Category: Gadelha, C A.A.]]
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[[Category: Gadelha, C A.A]]
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[[Category: Nobrega, R B.]]
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[[Category: Nobrega, R B]]
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[[Category: Rocha, B A.M.]]
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[[Category: Rocha, B A.M]]
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[[Category: Salviano, E.]]
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[[Category: Salviano, E]]
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[[Category: Santi-Gadelha, T.]]
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[[Category: Santi-Gadelha, T]]
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[[Category: Silva-Filho, J C.]]
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[[Category: Silva-Filho, J C]]
[[Category: Beta-sandwich]]
[[Category: Beta-sandwich]]
[[Category: Carbohydrate-binding protein]]
[[Category: Carbohydrate-binding protein]]

Revision as of 12:31, 4 January 2015

Crystal structure of Canavalia brasiliensis seed lectin (ConBr) in complex with beta-d-ribofuranose

4h55, resolution 2.15Å

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