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2gys
From Proteopedia
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| - | [[Image:2gys.gif|left|200px]] | + | [[Image:2gys.gif|left|200px]] |
| - | + | ||
| - | '''2.7 A structure of the extracellular domains of the human beta common receptor involved in IL-3, IL-5, and GM-CSF signalling''' | + | {{Structure |
| + | |PDB= 2gys |SIZE=350|CAPTION= <scene name='initialview01'>2gys</scene>, resolution 2.70Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= CSF2RB, IL3RB, IL5RB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | }} | ||
| + | |||
| + | '''2.7 A structure of the extracellular domains of the human beta common receptor involved in IL-3, IL-5, and GM-CSF signalling''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2GYS is a [ | + | 2GYS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GYS OCA]. |
==Reference== | ==Reference== | ||
| - | An improved resolution structure of the human beta common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitope., Carr PD, Conlan F, Ford S, Ollis DL, Young IG, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jun 1;62(Pt, 6):509-13. Epub 2006 May 31. PMID:[http:// | + | An improved resolution structure of the human beta common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitope., Carr PD, Conlan F, Ford S, Ollis DL, Young IG, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jun 1;62(Pt, 6):509-13. Epub 2006 May 31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16754968 16754968] |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| Line 18: | Line 27: | ||
[[Category: Ollis, D L.]] | [[Category: Ollis, D L.]] | ||
[[Category: Young, I G.]] | [[Category: Young, I G.]] | ||
| - | [[Category: dimer of interlocking chains of fibronectin-iii | + | [[Category: dimer of interlocking chains of fibronectin-iii domain]] |
[[Category: four fibronectin-iii domains per chain]] | [[Category: four fibronectin-iii domains per chain]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:10:27 2008'' |
Revision as of 15:10, 20 March 2008
| |||||||
| , resolution 2.70Å | |||||||
|---|---|---|---|---|---|---|---|
| Gene: | CSF2RB, IL3RB, IL5RB (Homo sapiens) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
2.7 A structure of the extracellular domains of the human beta common receptor involved in IL-3, IL-5, and GM-CSF signalling
Overview
X-ray diffraction has been used to produce and refine a model of the extracellular domains of the beta common cytokine receptor. A minor improvement in resolution has resulted in improved electron-density maps, which have given a clearer indication of the position and stabilization of the key residues Tyr15, Phe79, Tyr347, His349, Ile350 and Tyr403 in the elbow region between domain 1 and domain 4 of the dimer-related molecule.
About this Structure
2GYS is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
An improved resolution structure of the human beta common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitope., Carr PD, Conlan F, Ford S, Ollis DL, Young IG, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jun 1;62(Pt, 6):509-13. Epub 2006 May 31. PMID:16754968
Page seeded by OCA on Thu Mar 20 17:10:27 2008
