4j1o
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal structure of an enolase (mandelate racemase subgroup) from paracococus denitrificans pd1222 (target nysgrc-012907) with bound l-proline betaine (substrate)== | |
| - | + | <StructureSection load='4j1o' size='340' side='right' caption='[[4j1o]], [[Resolution|resolution]] 1.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4j1o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Paracoccus_denitrificans_pd1222 Paracoccus denitrificans pd1222]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J1O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J1O FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PBE:1,1-DIMETHYL-PROLINIUM'>PBE</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j1o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j1o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4j1o RCSB], [http://www.ebi.ac.uk/pdbsum/4j1o PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | == | + | == Function == |
| - | [[4j1o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Paracoccus_denitrificans_pd1222 Paracoccus denitrificans pd1222]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J1O OCA]. | + | [[http://www.uniprot.org/uniprot/A1B198_PARDP A1B198_PARDP]] Catalyzes the 2-epimerization of trans-4-hydroxy-L-proline betaine (tHyp-B) to cis-4-hydroxy-D-proline betaine (cHyp-B). Is involved in a catabolic pathway that degrades tHyp-B to alpha-ketoglutarate. This pathway would permit the utilization of tHyp-B as a carbon and nitrogen source in the absence of osmotic stress, since tHyp-B functions as an osmolyte and is not catabolized when it is needed as osmoprotectant. Can also catalyze the racemization of L-proline betaine.<ref>PMID:24056934</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Paracoccus denitrificans pd1222]] | [[Category: Paracoccus denitrificans pd1222]] | ||
| - | [[Category: Almo, S C | + | [[Category: Almo, S C]] |
| - | [[Category: Bhosle, R | + | [[Category: Bhosle, R]] |
| - | [[Category: Bonanno, J B | + | [[Category: Bonanno, J B]] |
| - | [[Category: Chamala, S | + | [[Category: Chamala, S]] |
| - | [[Category: Evans, B | + | [[Category: Evans, B]] |
| - | [[Category: Gerlt, J A | + | [[Category: Gerlt, J A]] |
| - | [[Category: Gizzi, A | + | [[Category: Gizzi, A]] |
| - | [[Category: Hammonds, J | + | [[Category: Hammonds, J]] |
| - | [[Category: Hillerich, B | + | [[Category: Hillerich, B]] |
| - | [[Category: Kar, A | + | [[Category: Kar, A]] |
| - | [[Category: LaFleur, J | + | [[Category: LaFleur, J]] |
| - | [[Category: Love, J | + | [[Category: Love, J]] |
| - | [[Category: Morisco, L L | + | [[Category: Morisco, L L]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Seidel, R D | + | [[Category: Seidel, R D]] |
| - | [[Category: Sojitra, S | + | [[Category: Sojitra, S]] |
| - | [[Category: Stead, M | + | [[Category: Stead, M]] |
| - | [[Category: Toro, R | + | [[Category: Toro, R]] |
| - | [[Category: Vetting, M W | + | [[Category: Vetting, M W]] |
| - | [[Category: Villigas, G | + | [[Category: Villigas, G]] |
| - | [[Category: Wasserman, S R | + | [[Category: Wasserman, S R]] |
[[Category: Betaine racemase]] | [[Category: Betaine racemase]] | ||
[[Category: Enolase]] | [[Category: Enolase]] | ||
[[Category: Isomerase]] | [[Category: Isomerase]] | ||
| - | [[Category: New york structural genomics research consortium]] | ||
[[Category: Nysgrc]] | [[Category: Nysgrc]] | ||
[[Category: Proline betaine racemease]] | [[Category: Proline betaine racemease]] | ||
[[Category: Psi-biology]] | [[Category: Psi-biology]] | ||
| - | [[Category: Structural genomic]] | ||
Revision as of 12:58, 4 January 2015
Crystal structure of an enolase (mandelate racemase subgroup) from paracococus denitrificans pd1222 (target nysgrc-012907) with bound l-proline betaine (substrate)
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Categories: Paracoccus denitrificans pd1222 | Almo, S C | Bhosle, R | Bonanno, J B | Chamala, S | Evans, B | Gerlt, J A | Gizzi, A | Hammonds, J | Hillerich, B | Kar, A | LaFleur, J | Love, J | Morisco, L L | Structural genomic | Seidel, R D | Sojitra, S | Stead, M | Toro, R | Vetting, M W | Villigas, G | Wasserman, S R | Betaine racemase | Enolase | Isomerase | Nysgrc | Proline betaine racemease | Psi-biology
