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4bk8
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| - | + | ==Superoxide reductase (Neelaredoxin) from Ignicoccus hospitalis== | |
| - | + | <StructureSection load='4bk8' size='340' side='right' caption='[[4bk8]], [[Resolution|resolution]] 1.85Å' scene=''> | |
| - | {{ | + | == Structural highlights == |
| + | <table><tr><td colspan='2'>[[4bk8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dsm_18386 Dsm 18386]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BK8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BK8 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bk8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bk8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bk8 RCSB], [http://www.ebi.ac.uk/pdbsum/4bk8 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Superoxide reductases (SORs) are metalloproteins which constitute the most recently identified oxygen-detoxification system in anaerobic and microaerobic bacteria and archaea. SORs are involved in scavenging superoxide radicals from the cell by catalyzing the reduction of superoxide ({\rm O}_{2};{\bullet -}) to hydrogen peroxide and are characterized by a catalytic nonhaem iron centre coordinated by four histidine ligands and one cysteine ligand. Ignicoccus hospitalis, a hyperthermophilic crenarchaeon, is known to have a neelaredoxin-type SOR that keeps toxic oxygen species levels under control. Blue crystals of recombinant I. hospitalis oxidized neelaredoxin (14.1 kDa, 124 residues) were obtained. These crystals diffracted to 2.4 A resolution in-house at room temperature and belonged to the hexagonal space group P6(2)22 or P6(4)22, with unit-cell parameters a = b = 108, c = 64 A. Cell-content analysis indicated the presence of one monomer in the asymmetric unit. | ||
| - | + | Cloning, purification, crystallization and X-ray crystallographic analysis of Ignicoccus hospitalis neelaredoxin.,Pinho FG, Romao CV, Pinto AF, Saraiva LM, Huber H, Matias PM, Teixeira M, Bandeiras TM Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 May 1;66(Pt 5):605-7. doi:, 10.1107/S1744309110012030. Epub 2010 Apr 30. PMID:20445270<ref>PMID:20445270</ref> | |
| - | + | ||
| - | == | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
| - | + | </div> | |
| - | [[Category: Bandeiras, T M | + | == References == |
| - | [[Category: Barradas, A R | + | <references/> |
| - | [[Category: Matias, P M | + | __TOC__ |
| - | [[Category: Pinho, F G | + | </StructureSection> |
| - | [[Category: Pinto, A F | + | [[Category: Dsm 18386]] |
| - | [[Category: Romao, C V | + | [[Category: Bandeiras, T M]] |
| - | [[Category: Sousa, C M | + | [[Category: Barradas, A R]] |
| - | [[Category: Teixeira, M | + | [[Category: Matias, P M]] |
| + | [[Category: Pinho, F G]] | ||
| + | [[Category: Pinto, A F]] | ||
| + | [[Category: Romao, C V]] | ||
| + | [[Category: Sousa, C M]] | ||
| + | [[Category: Teixeira, M]] | ||
[[Category: Neelaredoxin]] | [[Category: Neelaredoxin]] | ||
[[Category: Oxidative stress]] | [[Category: Oxidative stress]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Symbiosis]] | [[Category: Symbiosis]] | ||
Revision as of 13:05, 4 January 2015
Superoxide reductase (Neelaredoxin) from Ignicoccus hospitalis
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