4iy4

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{{STRUCTURE_4iy4| PDB=4iy4 | SCENE= }}
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==Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4==
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===Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4===
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<StructureSection load='4iy4' size='340' side='right' caption='[[4iy4]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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== Structural highlights ==
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==Disease==
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<table><tr><td colspan='2'>[[4iy4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IY4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IY4 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4iy0|4iy0]], [[4iy2|4iy2]], [[4iy3|4iy3]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CNNM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iy4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4iy4 RCSB], [http://www.ebi.ac.uk/pdbsum/4iy4 PDBsum]</span></td></tr>
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</table>
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== Disease ==
[[http://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN]] Familial primary hypomagnesemia with normocalcuria and normocalcemia. The disease is caused by mutations affecting the gene represented in this entry.
[[http://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN]] Familial primary hypomagnesemia with normocalcuria and normocalcemia. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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==Function==
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[[http://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN]] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity).
[[http://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN]] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity).
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4iy4]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IY4 OCA].
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[[Category: Human]]
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[[Category: Accardi, A.]]
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[[Category: Accardi, A]]
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[[Category: Corral-Rodriguez, M A.]]
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[[Category: Corral-Rodriguez, M A]]
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[[Category: Diercks, T.]]
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[[Category: Diercks, T]]
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[[Category: Encinar, J A.]]
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[[Category: Encinar, J A]]
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[[Category: Ereno-Orbea, J.]]
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[[Category: Ereno-Orbea, J]]
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[[Category: Gomez-Garcia, I.]]
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[[Category: Gomez-Garcia, I]]
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[[Category: Martinez-Cruz, L A.]]
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[[Category: Martinez-Cruz, L A]]
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[[Category: Muller, D.]]
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[[Category: Muller, D]]
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[[Category: Oyenarte, I.]]
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[[Category: Oyenarte, I]]
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[[Category: Spiwok, V.]]
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[[Category: Spiwok, V]]
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[[Category: Stuiver, M.]]
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[[Category: Stuiver, M]]
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[[Category: Terashima, H.]]
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[[Category: Terashima, H]]
[[Category: Bateman domain]]
[[Category: Bateman domain]]
[[Category: Cbs domain]]
[[Category: Cbs domain]]

Revision as of 13:33, 4 January 2015

Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4

4iy4, resolution 2.90Å

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