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4c6y

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4c6y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C6Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C6Y FirstGlance]. <br>
<table><tr><td colspan='2'>[[4c6y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C6Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C6Y FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4c75|4c75]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4c75|4c75]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c6y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c6y RCSB], [http://www.ebi.ac.uk/pdbsum/4c6y PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c6y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c6y RCSB], [http://www.ebi.ac.uk/pdbsum/4c6y PDBsum]</span></td></tr>
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<table>
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</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Phenotypic comparisons of consensus variants versus laboratory resurrections of Precambrian proteins.,Risso VA, Gavira JA, Gaucher EA, Sanchez-Ruiz JM Proteins. 2014 Apr 8. doi: 10.1002/prot.24575. PMID:24710963<ref>PMID:24710963</ref>
Phenotypic comparisons of consensus variants versus laboratory resurrections of Precambrian proteins.,Risso VA, Gavira JA, Gaucher EA, Sanchez-Ruiz JM Proteins. 2014 Apr 8. doi: 10.1002/prot.24575. PMID:24710963<ref>PMID:24710963</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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[[Category: Beta-lactamase]]
[[Category: Beta-lactamase]]
[[Category: Synthetic construct sequences]]
[[Category: Synthetic construct sequences]]
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[[Category: Gavira, J A.]]
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[[Category: Gavira, J A]]
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[[Category: Risso, V A.]]
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[[Category: Risso, V A]]
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[[Category: Sanchez-Ruiz, J M.]]
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[[Category: Sanchez-Ruiz, J M]]
[[Category: Antibiotic resistance]]
[[Category: Antibiotic resistance]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]

Revision as of 13:58, 4 January 2015

Ancestral PNCA (last common ancestors of Gram-positive and Gram- negative bacteria) beta-lactamase class A

4c6y, resolution 1.80Å

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