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4cmf

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<StructureSection load='4cmf' size='340' side='right' caption='[[4cmf]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='4cmf' size='340' side='right' caption='[[4cmf]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4cmf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusso Fusso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CMF OCA]. <br>
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<table><tr><td colspan='2'>[[4cmf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusso Fusso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CMF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CMF FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PXG:3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC+ACID'>PXG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PXG:3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC+ACID'>PXG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cmd|4cmd]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cmd|4cmd]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Branched-chain-amino-acid_transaminase Branched-chain-amino-acid transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.42 2.6.1.42] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cmf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cmf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cmf RCSB], [http://www.ebi.ac.uk/pdbsum/4cmf PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cmf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cmf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cmf RCSB], [http://www.ebi.ac.uk/pdbsum/4cmf PDBsum]</span></td></tr>
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<table>
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</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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The substrate specificity, enantioselectivity and structure of the (R)-selective amine:pyruvate transaminase from Nectria haematococca.,Sayer C, Martinez-Torres RJ, Richter N, Isupov MN, Hailes HC, Littlechild JA, Ward JM FEBS J. 2014 Mar 11. doi: 10.1111/febs.12778. PMID:24618038<ref>PMID:24618038</ref>
The substrate specificity, enantioselectivity and structure of the (R)-selective amine:pyruvate transaminase from Nectria haematococca.,Sayer C, Martinez-Torres RJ, Richter N, Isupov MN, Hailes HC, Littlechild JA, Ward JM FEBS J. 2014 Mar 11. doi: 10.1111/febs.12778. PMID:24618038<ref>PMID:24618038</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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[[Category: Branched-chain-amino-acid transaminase]]
[[Category: Branched-chain-amino-acid transaminase]]
[[Category: Fusso]]
[[Category: Fusso]]
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[[Category: Hailes, H C.]]
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[[Category: Hailes, H C]]
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[[Category: Isupov, M.]]
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[[Category: Isupov, M]]
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[[Category: Littlechild, J.]]
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[[Category: Littlechild, J]]
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[[Category: Martinez-Torres, R J.]]
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[[Category: Martinez-Torres, R J]]
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[[Category: Richter, N.]]
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[[Category: Richter, N]]
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[[Category: Sayer, C.]]
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[[Category: Sayer, C]]
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[[Category: Ward, J.]]
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[[Category: Ward, J]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 14:05, 4 January 2015

The (R)-selective transaminase from Nectria haematococca with inhibitor bound

4cmf, resolution 1.50Å

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