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4erq

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4erq]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ERQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ERQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[4erq]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ERQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ERQ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ery|4ery]], [[4erz|4erz]], [[4es0|4es0]], [[4esg|4esg]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ery|4ery]], [[4erz|4erz]], [[4es0|4es0]], [[4esg|4esg]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BIG3, WDR5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BIG3, WDR5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4erq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4erq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4erq RCSB], [http://www.ebi.ac.uk/pdbsum/4erq PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4erq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4erq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4erq RCSB], [http://www.ebi.ac.uk/pdbsum/4erq PDBsum]</span></td></tr>
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<table>
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</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/MLL2_HUMAN MLL2_HUMAN]] Kabuki syndrome. The disease is caused by mutations affecting the gene represented in this entry.
[[http://www.uniprot.org/uniprot/MLL2_HUMAN MLL2_HUMAN]] Kabuki syndrome. The disease is caused by mutations affecting the gene represented in this entry.
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[[Category: Histone-lysine N-methyltransferase]]
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Cosgrove, M S.]]
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[[Category: Cosgrove, M S]]
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[[Category: Dharmarajan, V.]]
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[[Category: Dharmarajan, V]]
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[[Category: Lee, J H.]]
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[[Category: Lee, J H]]
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[[Category: Patel, A.]]
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[[Category: Patel, A]]
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[[Category: Skalnik, D G.]]
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[[Category: Skalnik, D G]]
[[Category: 3-10 helix]]
[[Category: 3-10 helix]]
[[Category: Ash2l]]
[[Category: Ash2l]]

Revision as of 14:09, 4 January 2015

X-ray structure of WDR5-MLL2 Win motif peptide binary complex

4erq, resolution 1.91Å

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