2h5z

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[[Image:2h5z.jpg|left|200px]]<br /><applet load="2h5z" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2h5z.jpg|left|200px]]
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caption="2h5z, resolution 1.92&Aring;" />
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'''Crystallographic structure of digestive lysozyme 1 from Musca domestica bound to chitotetraose at 1.92 A resolution'''<br />
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{{Structure
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|PDB= 2h5z |SIZE=350|CAPTION= <scene name='initialview01'>2h5z</scene>, resolution 1.92&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=CTO:TRIACETYLCHITOTRIOSE'>CTO</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17]
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|GENE=
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}}
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'''Crystallographic structure of digestive lysozyme 1 from Musca domestica bound to chitotetraose at 1.92 A resolution'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2H5Z is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Musca_domestica Musca domestica] with <scene name='pdbligand=CTO:'>CTO</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H5Z OCA].
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2H5Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Musca_domestica Musca domestica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H5Z OCA].
==Reference==
==Reference==
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Crystallization, data collection and phasing of two digestive lysozymes from Musca domestica., Marana SR, Cancado FC, Valerio AA, Ferreira C, Terra WR, Barbosa JA, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Aug 1;62(Pt, 8):750-2. Epub 2006 Jul 24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16880547 16880547]
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Crystallization, data collection and phasing of two digestive lysozymes from Musca domestica., Marana SR, Cancado FC, Valerio AA, Ferreira C, Terra WR, Barbosa JA, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Aug 1;62(Pt, 8):750-2. Epub 2006 Jul 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16880547 16880547]
[[Category: Lysozyme]]
[[Category: Lysozyme]]
[[Category: Musca domestica]]
[[Category: Musca domestica]]
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[[Category: musca domestica]]
[[Category: musca domestica]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:38:35 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:13:07 2008''

Revision as of 15:13, 20 March 2008


PDB ID 2h5z

Drag the structure with the mouse to rotate
, resolution 1.92Å
Ligands:
Activity: Lysozyme, with EC number 3.2.1.17
Coordinates: save as pdb, mmCIF, xml



Crystallographic structure of digestive lysozyme 1 from Musca domestica bound to chitotetraose at 1.92 A resolution


Overview

Lysozymes are mostly known for their defensive role against bacteria, but in several animals lysozymes have a digestive function. Here, the initial crystallographic characterization of two digestive lysozymes from Musca domestica are presented. The proteins were crystallized using the sitting-drop vapour-diffusion method in the presence of ammonium sulfate or PEG/2-propanol as the precipitant. X-ray diffraction data were collected to a maximum resolution of 1.9 angstroms using synchrotron radiation. The lysozyme 1 and 2 crystals belong to the monoclinic space group P2(1) (unit-cell parameters a = 36.52, b = 79.44, c = 45.20 angstroms, beta = 102.97 degrees) and the orthorhombic space group P2(1)2(1)2 (unit-cell parameters a = 73.90, b = 96.40, c = 33.27 angstroms), respectively. The crystal structures were solved by molecular replacement and structure refinement is in progress.

About this Structure

2H5Z is a Single protein structure of sequence from Musca domestica. Full crystallographic information is available from OCA.

Reference

Crystallization, data collection and phasing of two digestive lysozymes from Musca domestica., Marana SR, Cancado FC, Valerio AA, Ferreira C, Terra WR, Barbosa JA, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Aug 1;62(Pt, 8):750-2. Epub 2006 Jul 24. PMID:16880547

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