Sandbox Reserved 966
From Proteopedia
(Difference between revisions)
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In the late 1960s, a Edward Schantz and a San Francisco opthalmologist, Alan Scott, start to work on the using of the botulinum toxin in therapeutic process. | In the late 1960s, a Edward Schantz and a San Francisco opthalmologist, Alan Scott, start to work on the using of the botulinum toxin in therapeutic process. | ||
First, they try to treat strabismus and in the late 1970s the neurotoxin is used in many therapeutic applications. | First, they try to treat strabismus and in the late 1970s the neurotoxin is used in many therapeutic applications. | ||
| - | === hyperhidrosis === | + | === hyperhidrosis and CHARGE syndrome === |
We can now treat excessive sweating with botulinium toxin thanks to his action on the receptors of the parasympathetic network. Excessive dribbling can be treated in the same way. | We can now treat excessive sweating with botulinium toxin thanks to his action on the receptors of the parasympathetic network. Excessive dribbling can be treated in the same way. | ||
=== Cosmetic === | === Cosmetic === | ||
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=== Blepharospesm, nystagmus, Torticollis and strabismus === | === Blepharospesm, nystagmus, Torticollis and strabismus === | ||
This pathologic can be treated by the same methode. Every anomalous behaviour of muscle tissue can be fixed thanks to the paralyzing effect of the toxin. It is based on the muscles relaxation. | This pathologic can be treated by the same methode. Every anomalous behaviour of muscle tissue can be fixed thanks to the paralyzing effect of the toxin. It is based on the muscles relaxation. | ||
| - | === UMN syndrome === | ||
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| - | === Chronic migraine === | ||
=== Cervical dystonia === | === Cervical dystonia === | ||
| + | BTX-A is used against cervical dystonia. But it can become inefficient after a periode of use. | ||
Revision as of 18:14, 4 January 2015
| This Sandbox is Reserved from 15/11/2014, through 15/05/2015 for use in the course "Biomolecule" taught by Bruno Kieffer at the Strasbourg University. This reservation includes Sandbox Reserved 951 through Sandbox Reserved 975. |
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Structure of the "Clostridium botulinum" neurotoxin serotype A light chain with Zn2+ cofactor bound
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