4l6b

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4l6b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L6B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L6B FirstGlance]. <br>
<table><tr><td colspan='2'>[[4l6b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L6B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L6B FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1VS:N-ETHYL-2-({N-[2-(1H-INDOL-3-YL)ETHYL]GLYCYL}AMINO)-4-PHENYLTHIOPHENE-3-CARBOXAMIDE'>1VS</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1VS:N-ETHYL-2-({N-[2-(1H-INDOL-3-YL)ETHYL]GLYCYL}AMINO)-4-PHENYLTHIOPHENE-3-CARBOXAMIDE'>1VS</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3t7x|3t7x]], [[4lap|4lap]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3t7x|3t7x]], [[4lap|4lap]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l6b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l6b RCSB], [http://www.ebi.ac.uk/pdbsum/4l6b PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l6b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l6b RCSB], [http://www.ebi.ac.uk/pdbsum/4l6b PDBsum]</span></td></tr>
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<table>
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</table>
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==See Also==
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*[[Pepsin|Pepsin]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cryphonectria parasitica]]
[[Category: Cryphonectria parasitica]]
[[Category: Endothiapepsin]]
[[Category: Endothiapepsin]]
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[[Category: Heine, A.]]
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[[Category: Heine, A]]
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[[Category: Klebe, G.]]
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[[Category: Klebe, G]]
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[[Category: Park, A.]]
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[[Category: Park, A]]
[[Category: Aspartate protease]]
[[Category: Aspartate protease]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Inhibitor complex]]
[[Category: Inhibitor complex]]

Revision as of 08:33, 5 January 2015

Endothiapepsin in complex with thiophen-based inhibitor SAP128

4l6b, resolution 1.37Å

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