2hbt

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[[Image:2hbt.gif|left|200px]]<br /><applet load="2hbt" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2hbt.gif|left|200px]]
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caption="2hbt, resolution 1.600&Aring;" />
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'''Crystal structure of HIF prolyl hydroxylase EGLN-1 in complex with a biologically active inhibitor'''<br />
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{{Structure
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|PDB= 2hbt |SIZE=350|CAPTION= <scene name='initialview01'>2hbt</scene>, resolution 1.600&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene> and <scene name='pdbligand=UN9:N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE'>UN9</scene>
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|ACTIVITY=
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|GENE= EGLN1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Crystal structure of HIF prolyl hydroxylase EGLN-1 in complex with a biologically active inhibitor'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2HBT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=FE2:'>FE2</scene> and <scene name='pdbligand=UN9:'>UN9</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HBT OCA].
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2HBT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HBT OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: prolyl hydroxylase]]
[[Category: prolyl hydroxylase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:40:14 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:15:08 2008''

Revision as of 15:15, 20 March 2008

Image:2hbt.gif


PDB ID 2hbt

Drag the structure with the mouse to rotate
, resolution 1.600Å
Ligands: and
Gene: EGLN1 (Homo sapiens)
Coordinates: save as pdb, mmCIF, xml



Crystal structure of HIF prolyl hydroxylase EGLN-1 in complex with a biologically active inhibitor


Disease

Known disease associated with this structure: Erythrocytosis, familial, 3 OMIM:[606425]

About this Structure

2HBT is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 17:15:08 2008

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OCA

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