4lgn
From Proteopedia
(Difference between revisions)
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| - | + | ==The structure of Acidothermus cellulolyticus family 74 glycoside hydrolase== | |
| - | + | <StructureSection load='4lgn' size='340' side='right' caption='[[4lgn]], [[Resolution|resolution]] 1.82Å' scene=''> | |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[4lgn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acic1 Acic1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LGN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LGN FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Acel_0618 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=351607 ACIC1])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lgn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lgn RCSB], [http://www.ebi.ac.uk/pdbsum/4lgn PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Here, a 1.82 A resolution X-ray structure of a glycoside hydrolase family 74 (GH74) enzyme from Acidothermus cellulolyticus is reported. The resulting structure was refined to an R factor of 0.150 and an Rfree of 0.196. Structural analysis shows that five related structures have been reported with a secondary-structure similarity of between 75 and 89%. The five similar structures were all either Clostridium thermocellum or Geotrichum sp. M128 GH74 xyloglucanases. Structural analysis indicates that the A. cellulolyticus GH74 enzyme is an endoxyloglucanase, as it lacks a characteristic loop that blocks one end of the active site in exoxyloglucanases. Superimposition with the C. thermocellum GH74 shows that Asp451 and Asp38 are the catalytic residues. | ||
| - | + | Structure of Acidothermus cellulolyticus family 74 glycoside hydrolase at 1.82 A resolution.,Alahuhta M, Adney WS, Himmel ME, Lunin VV Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Dec;69(Pt 12):1335-8. doi:, 10.1107/S1744309113030005. Epub 2013 Nov 28. PMID:24316824<ref>PMID:24316824</ref> | |
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| - | == | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
| - | + | </div> | |
| - | [[Category: Alahuhta, P M | + | == References == |
| - | [[Category: Lunin, V V | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Acic1]] | ||
| + | [[Category: Alahuhta, P M]] | ||
| + | [[Category: Lunin, V V]] | ||
[[Category: Cellulose binding protein]] | [[Category: Cellulose binding protein]] | ||
[[Category: Gh74]] | [[Category: Gh74]] | ||
[[Category: Xyloglucanase]] | [[Category: Xyloglucanase]] | ||
Revision as of 09:10, 5 January 2015
The structure of Acidothermus cellulolyticus family 74 glycoside hydrolase
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