4m5n
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4m5n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M5N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M5N FirstGlance]. <br> | <table><tr><td colspan='2'>[[4m5n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M5N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M5N FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=YH7:6-AMINO-1,9-DIHYDRO-2H-PURINE-2-THIONE'>YH7</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=YH7:6-AMINO-1,9-DIHYDRO-2H-PURINE-2-THIONE'>YH7</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1q0n|1q0n]], [[1hka|1hka]], [[1kbr|1kbr]], [[4m5g|4m5g]], [[4m5h|4m5h]], [[4m5i|4m5i]], [[4m5j|4m5j]], [[4m5k|4m5k]], [[4m5l|4m5l]], [[4m5m|4m5m]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1q0n|1q0n]], [[1hka|1hka]], [[1kbr|1kbr]], [[4m5g|4m5g]], [[4m5h|4m5h]], [[4m5i|4m5i]], [[4m5j|4m5j]], [[4m5k|4m5k]], [[4m5l|4m5l]], [[4m5m|4m5m]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">folK, b0142, JW0138 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">folK, b0142, JW0138 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine_diphosphokinase 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.6.3 2.7.6.3] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine_diphosphokinase 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.6.3 2.7.6.3] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m5n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m5n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m5n RCSB], [http://www.ebi.ac.uk/pdbsum/4m5n PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m5n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m5n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m5n RCSB], [http://www.ebi.ac.uk/pdbsum/4m5n PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[6-hydroxymethyl-7%2C8-dihydropterin pyrophosphokinase|6-hydroxymethyl-7%2C8-dihydropterin pyrophosphokinase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]] | [[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]] | ||
[[Category: Ecoli]] | [[Category: Ecoli]] | ||
| - | [[Category: Hoagland, D | + | [[Category: Hoagland, D]] |
| - | [[Category: Kumar, G | + | [[Category: Kumar, G]] |
| - | [[Category: Lee, R E | + | [[Category: Lee, R E]] |
| - | [[Category: Rock, C O | + | [[Category: Rock, C O]] |
| - | [[Category: Waddell, B | + | [[Category: Waddell, B]] |
| - | [[Category: White, S W | + | [[Category: White, S W]] |
| - | [[Category: Yun, M | + | [[Category: Yun, M]] |
[[Category: Atp binding]] | [[Category: Atp binding]] | ||
[[Category: Diphosphotransferase]] | [[Category: Diphosphotransferase]] | ||
Revision as of 09:23, 5 January 2015
The Identification, Analysis and Structure-Based Development of Novel Inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase
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