2hek
From Proteopedia
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| - | [[Image:2hek.gif|left|200px]] | + | [[Image:2hek.gif|left|200px]] |
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| - | '''Crystal structure of O67745, a hypothetical protein from Aquifex aeolicus at 2.0 A resolution.''' | + | {{Structure |
| + | |PDB= 2hek |SIZE=350|CAPTION= <scene name='initialview01'>2hek</scene>, resolution 1.997Å | ||
| + | |SITE= <scene name='pdbsite=AC1:Po4+Binding+Site+For+Residue+A+501'>AC1</scene>, <scene name='pdbsite=AC2:Po4+Binding+Site+For+Residue+B+502'>AC2</scene>, <scene name='pdbsite=AC3:Po4+Binding+Site+For+Residue+B+503'>AC3</scene>, <scene name='pdbsite=AC4:Po4+Binding+Site+For+Residue+B+504'>AC4</scene>, <scene name='pdbsite=AC5:Zn+Binding+Site+For+Residue+B+601'>AC5</scene>, <scene name='pdbsite=AC6:Zn+Binding+Site+For+Residue+A+602'>AC6</scene>, <scene name='pdbsite=AC7:Br+Binding+Site+For+Residue+B+603'>AC7</scene>, <scene name='pdbsite=AC8:Cl+Binding+Site+For+Residue+A+604'>AC8</scene>, <scene name='pdbsite=AC9:Cl+Binding+Site+For+Residue+B+605'>AC9</scene>, <scene name='pdbsite=BC1:Cl+Binding+Site+For+Residue+A+606'>BC1</scene>, <scene name='pdbsite=BC2:Cl+Binding+Site+For+Residue+B+607'>BC2</scene>, <scene name='pdbsite=BC3:Cl+Binding+Site+For+Residue+B+608'>BC3</scene>, <scene name='pdbsite=BC4:Gdp+Binding+Site+For+Residue+A+401'>BC4</scene>, <scene name='pdbsite=BC5:Gdp+Binding+Site+For+Residue+A+402'>BC5</scene>, <scene name='pdbsite=BC6:Gol+Binding+Site+For+Residue+A+403'>BC6</scene>, <scene name='pdbsite=BC7:Gol+Binding+Site+For+Residue+A+404'>BC7</scene>, <scene name='pdbsite=BC8:Gol+Binding+Site+For+Residue+B+405'>BC8</scene>, <scene name='pdbsite=BC9:Gol+Binding+Site+For+Residue+A+406'>BC9</scene>, <scene name='pdbsite=CC1:Gol+Binding+Site+For+Residue+A+407'>CC1</scene>, <scene name='pdbsite=CC2:Gol+Binding+Site+For+Residue+A+408'>CC2</scene>, <scene name='pdbsite=CC3:Gol+Binding+Site+For+Residue+B+409'>CC3</scene> and <scene name='pdbsite=CC4:Gol+Binding+Site+For+Residue+A+410'>CC4</scene> | ||
| + | |LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=GDP:GUANOSINE-5'-DIPHOSPHATE'>GDP</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''Crystal structure of O67745, a hypothetical protein from Aquifex aeolicus at 2.0 A resolution.''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2HEK is a [ | + | 2HEK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HEK OCA]. |
==Reference== | ==Reference== | ||
| - | Structure of O67745_AQUAE, a hypothetical protein from Aquifex aeolicus., Oganesyan V, Adams PD, Jancarik J, Kim R, Kim SH, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 May 1;63(Pt, 5):369-74. Epub 2007 Apr 28. PMID:[http:// | + | Structure of O67745_AQUAE, a hypothetical protein from Aquifex aeolicus., Oganesyan V, Adams PD, Jancarik J, Kim R, Kim SH, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 May 1;63(Pt, 5):369-74. Epub 2007 Apr 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17565173 17565173] |
[[Category: Aquifex aeolicus]] | [[Category: Aquifex aeolicus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: protein structure initiative]] | [[Category: protein structure initiative]] | ||
[[Category: psi]] | [[Category: psi]] | ||
| - | [[Category: structural | + | [[Category: structural genomic]] |
[[Category: unknown function]] | [[Category: unknown function]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:16:02 2008'' |
Revision as of 15:16, 20 March 2008
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| , resolution 1.997Å | |||||||
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| Sites: | , , , , , , , , , , , , , , , , , , , , and | ||||||
| Ligands: | , , , , and | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of O67745, a hypothetical protein from Aquifex aeolicus at 2.0 A resolution.
Overview
Using single-wavelength anomalous dispersion data obtained from a gold-derivatized crystal, the X-ray crystal structure of the protein 067745_AQUAE from the prokaryotic organism Aquifex aeolicus has been determined to a resolution of 2.0 A. Amino-acid residues 1-371 of the 44 kDa protein were identified by Pfam as an HD domain and a member of the metal-dependent phosphohydrolase superfamily (accession No. PF01966). Although three families from this large and diverse group of enzymatic proteins are represented in the PDB, the structure of 067745_AQUAE reveals a unique fold that is unlike the others and that is likely to represent a new subfamily, further organizing the families and characterizing the proteins. Data are presented that provide the first insights into the structural organization of the proteins within this clan and a distal alternative GDP-binding domain outside the metal-binding active site is proposed.
About this Structure
2HEK is a Single protein structure of sequence from Aquifex aeolicus. Full crystallographic information is available from OCA.
Reference
Structure of O67745_AQUAE, a hypothetical protein from Aquifex aeolicus., Oganesyan V, Adams PD, Jancarik J, Kim R, Kim SH, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 May 1;63(Pt, 5):369-74. Epub 2007 Apr 28. PMID:17565173
Page seeded by OCA on Thu Mar 20 17:16:02 2008
Categories: Aquifex aeolicus | Single protein | Adams, P D. | BSGC, Berkeley Structural Genomics Center. | Jancarik, J. | Kim, R. | Kim, S H. | Oganesyan, V. | BR | CL | GDP | GOL | PO4 | ZN | Berkeley structural genomics center | Bsgc | Predominantly alpha helical protein with gdp binding site and active site being far from each other | Protein structure initiative | Psi | Structural genomic | Unknown function
