4o9s

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4o9s]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O9S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O9S FirstGlance]. <br>
<table><tr><td colspan='2'>[[4o9s]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O9S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O9S FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2RY:1-[4-(8LAMBDA~4~-CYCLOPENTA[4,5]THIENO[2,3-D]PYRIMIDIN-4-YL)PIPERAZIN-1-YL]-2-[2-(TRIFLUOROMETHYL)PHENYL]ETHANONE'>2RY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene><br>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2RY:1-[4-(8LAMBDA~4~-CYCLOPENTA[4,5]THIENO[2,3-D]PYRIMIDIN-4-YL)PIPERAZIN-1-YL]-2-[2-(TRIFLUOROMETHYL)PHENYL]ETHANONE'>2RY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fmz|3fmz]], [[4psq|4psq]]</td></tr>
+
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fmz|3fmz]], [[4psq|4psq]]</td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o9s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o9s RCSB], [http://www.ebi.ac.uk/pdbsum/4o9s PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o9s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o9s RCSB], [http://www.ebi.ac.uk/pdbsum/4o9s PDBsum]</span></td></tr>
-
<table>
+
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/RET4_HUMAN RET4_HUMAN]] Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:[http://omim.org/entry/180250 180250]]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.
[[http://www.uniprot.org/uniprot/RET4_HUMAN RET4_HUMAN]] Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:[http://omim.org/entry/180250 180250]]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.
Line 23: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Johnstone, S.]]
+
[[Category: Johnstone, S]]
-
[[Category: Walker, N P.]]
+
[[Category: Walker, N P]]
-
[[Category: Wang, Z.]]
+
[[Category: Wang, Z]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Protein binding]]
[[Category: Protein binding]]

Revision as of 09:41, 5 January 2015

Crystal structure of Retinol-Binding Protein 4 (RBP4)in complex with a non-retinoid ligand

4o9s, resolution 2.30Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools