4ok0
From Proteopedia
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| - | + | ==Crystal structure of putative nucleotidyltransferase from H. pylori== | |
| - | === | + | <StructureSection load='4ok0' size='340' side='right' caption='[[4ok0]], [[Resolution|resolution]] 2.17Å' scene=''> |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[4ok0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori_j99 Campylobacter pylori j99]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OK0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OK0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">jhp_0933 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=85963 Campylobacter pylori J99])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ok0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ok0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ok0 RCSB], [http://www.ebi.ac.uk/pdbsum/4ok0 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The jhp0933 gene in the plasticity region of Helicobacter pylori J99 encodes a hypothetical protein (JHP933), which may play some roles in pathogenesis. Here, we have determined the crystal structure of JHP933 at 2.17 A. It represents the first crystal structure of the DUF1814 protein family. JHP933 consists of two domains: an N-terminal domain of the nucleotidyltransferase (NTase) fold and a C-terminal helix bundle domain. A highly positively-charged surface patch exists adjacent to the putative NTP binding site. Structural similarity of JHP933 to known NTases is very remote, suggesting that it may function as a novel nucleotidyltransferase. (c) Proteins 2014;. (c) 2014 Wiley Periodicals, Inc. | ||
| - | + | Crystal structure of JHP933 from Helicobacter pylori J99 shows two-domain architecture with a DUF1814 family nucleotidyltransferase domain and a helical bundle domain.,Yoon JY, Lee SJ, Kim DJ, Lee BJ, Yang JK, Suh SW Proteins. 2014 Mar 27. doi: 10.1002/prot.24572. PMID:24677396<ref>PMID:24677396</ref> | |
| - | + | ||
| - | == | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
| - | + | </div> | |
| - | [[Category: Lee, B | + | == References == |
| - | [[Category: Lee, S J | + | <references/> |
| - | [[Category: Suh, S W | + | __TOC__ |
| - | [[Category: Yang, J K | + | </StructureSection> |
| - | [[Category: Yoon, J Y | + | [[Category: Campylobacter pylori j99]] |
| + | [[Category: Lee, B]] | ||
| + | [[Category: Lee, S J]] | ||
| + | [[Category: Suh, S W]] | ||
| + | [[Category: Yang, J K]] | ||
| + | [[Category: Yoon, J Y]] | ||
[[Category: Nucleotidyltransferase]] | [[Category: Nucleotidyltransferase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 09:46, 5 January 2015
Crystal structure of putative nucleotidyltransferase from H. pylori
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