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4ooa
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4ooa]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OOA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OOA FirstGlance]. <br> | <table><tr><td colspan='2'>[[4ooa]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OOA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OOA FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4oo7|4oo7]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4oo7|4oo7]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ooa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ooa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ooa RCSB], [http://www.ebi.ac.uk/pdbsum/4ooa PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ooa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ooa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ooa RCSB], [http://www.ebi.ac.uk/pdbsum/4ooa PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/CISD2_HUMAN CISD2_HUMAN]] Defects in CISD2 are the cause of Wolfram syndrome type 2 (WFS2) [MIM:[http://omim.org/entry/604928 604928]]. A rare disorder characterized by juvenile-onset insulin-dependent diabetes mellitus with optic atrophy. Other manifestations include diabetes insipidus, sensorineural deafness, dementia, psychiatric illnesses. WFS2 patients additionally show a strong bleeding tendency and gastrointestinal ulceration. Diabetes insipidus may be absent.<ref>PMID:17846994</ref> | [[http://www.uniprot.org/uniprot/CISD2_HUMAN CISD2_HUMAN]] Defects in CISD2 are the cause of Wolfram syndrome type 2 (WFS2) [MIM:[http://omim.org/entry/604928 604928]]. A rare disorder characterized by juvenile-onset insulin-dependent diabetes mellitus with optic atrophy. Other manifestations include diabetes insipidus, sensorineural deafness, dementia, psychiatric illnesses. WFS2 patients additionally show a strong bleeding tendency and gastrointestinal ulceration. Diabetes insipidus may be absent.<ref>PMID:17846994</ref> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Conlan, A R | + | [[Category: Conlan, A R]] |
| - | [[Category: Eisenberg-Domovich, Y | + | [[Category: Eisenberg-Domovich, Y]] |
| - | [[Category: Jennings, P A | + | [[Category: Jennings, P A]] |
| - | [[Category: Lipper, C H | + | [[Category: Lipper, C H]] |
| - | [[Category: Livnah, O | + | [[Category: Livnah, O]] |
| - | [[Category: Mittler, R | + | [[Category: Mittler, R]] |
| - | [[Category: Nechushtai, R | + | [[Category: Nechushtai, R]] |
| - | [[Category: Paddock, M L | + | [[Category: Paddock, M L]] |
| - | [[Category: Stofleth, J T | + | [[Category: Stofleth, J T]] |
| - | [[Category: Tamir, S | + | [[Category: Tamir, S]] |
[[Category: Membrane bound]] | [[Category: Membrane bound]] | ||
[[Category: Metal binding protein]] | [[Category: Metal binding protein]] | ||
[[Category: Oxidative stress]] | [[Category: Oxidative stress]] | ||
[[Category: Thiazolidinedione]] | [[Category: Thiazolidinedione]] | ||
Revision as of 09:52, 5 January 2015
CRYSTAL STRUCTURE of NAF1 (MINER1): H114C THE REDOX-ACTIVE 2FE-2S PROTEIN
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