4a2u
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4a2u]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A2U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A2U FirstGlance]. <br> | <table><tr><td colspan='2'>[[4a2u]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A2U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A2U FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a2u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a2u RCSB], [http://www.ebi.ac.uk/pdbsum/4a2u PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a2u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a2u RCSB], [http://www.ebi.ac.uk/pdbsum/4a2u PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/O69644_MYCTU O69644_MYCTU]] Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites, causing DNA-bending, to regulate transcription. cAMP improves binding to specific DNA sequences, probably by altering protein conformation. Activates expression of whiB1.<ref>PMID:16946269</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Myctu]] | [[Category: Myctu]] | ||
| - | [[Category: Gallagher, D T | + | [[Category: Gallagher, D T]] |
| - | [[Category: Reddy, P T | + | [[Category: Reddy, P T]] |
[[Category: Allostery]] | [[Category: Allostery]] | ||
[[Category: Catabolite gene activator protein]] | [[Category: Catabolite gene activator protein]] | ||
Revision as of 12:25, 5 January 2015
CRP(CAP) from Myco. Tuberculosis, with cAMP
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