3g0s

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[[Image:3g0s.png|left|200px]]
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==Dihydrodipicolinate synthase from Salmonella typhimurium LT2==
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<StructureSection load='3g0s' size='340' side='right' caption='[[3g0s]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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{{STRUCTURE_3g0s| PDB=3g0s | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3g0s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G0S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G0S FirstGlance]. <br>
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===Dihydrodipicolinate synthase from Salmonella typhimurium LT2===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yxc|1yxc]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dapA, STM2489 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2])</td></tr>
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==About this Structure==
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrodipicolinate_synthase Dihydrodipicolinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.52 4.2.1.52] </span></td></tr>
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[[3g0s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G0S OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g0s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g0s RCSB], [http://www.ebi.ac.uk/pdbsum/3g0s PDBsum], [http://www.topsan.org/Proteins/CSGID/3g0s TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DAPA_SALTY DAPA_SALTY]] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).[HAMAP-Rule:MF_00418]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g0/3g0s_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Dihydrodipicolinate Synthase|Dihydrodipicolinate Synthase]]
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*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
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__TOC__
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</StructureSection>
[[Category: Dihydrodipicolinate synthase]]
[[Category: Dihydrodipicolinate synthase]]
[[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]]
[[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]]
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[[Category: Anderson, W F.]]
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[[Category: Anderson, W F]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Structural genomic]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak, A]]
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[[Category: Maltseva, N.]]
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[[Category: Maltseva, N]]
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[[Category: Osipiuk, J.]]
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[[Category: Osipiuk, J]]
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[[Category: Stam, J.]]
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[[Category: Stam, J]]
[[Category: Amino-acid biosynthesis]]
[[Category: Amino-acid biosynthesis]]
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[[Category: Center for structural genomics of infectious disease]]
 
[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Diaminopimelate biosynthesis]]
[[Category: Diaminopimelate biosynthesis]]
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[[Category: Dihydrodipicolinate synthase]]
 
[[Category: Idp01004]]
[[Category: Idp01004]]
[[Category: Lyase]]
[[Category: Lyase]]
[[Category: Lysine biosynthesis]]
[[Category: Lysine biosynthesis]]
[[Category: Schiff base]]
[[Category: Schiff base]]
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[[Category: Structural genomic]]
 

Revision as of 12:52, 5 January 2015

Dihydrodipicolinate synthase from Salmonella typhimurium LT2

3g0s, resolution 1.85Å

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