3g0s
From Proteopedia
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- | + | ==Dihydrodipicolinate synthase from Salmonella typhimurium LT2== | |
- | + | <StructureSection load='3g0s' size='340' side='right' caption='[[3g0s]], [[Resolution|resolution]] 1.85Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[3g0s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G0S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G0S FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
- | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yxc|1yxc]]</td></tr> | |
- | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dapA, STM2489 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2])</td></tr> | |
- | == | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrodipicolinate_synthase Dihydrodipicolinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.52 4.2.1.52] </span></td></tr> |
- | [[3g0s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G0S OCA]. | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g0s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g0s RCSB], [http://www.ebi.ac.uk/pdbsum/3g0s PDBsum], [http://www.topsan.org/Proteins/CSGID/3g0s TOPSAN]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/DAPA_SALTY DAPA_SALTY]] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).[HAMAP-Rule:MF_00418] | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g0/3g0s_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
- | *[[Dihydrodipicolinate | + | *[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]] |
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Dihydrodipicolinate synthase]] | [[Category: Dihydrodipicolinate synthase]] | ||
[[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]] | [[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]] | ||
- | [[Category: Anderson, W F | + | [[Category: Anderson, W F]] |
- | [[Category: | + | [[Category: Structural genomic]] |
- | [[Category: Joachimiak, A | + | [[Category: Joachimiak, A]] |
- | [[Category: Maltseva, N | + | [[Category: Maltseva, N]] |
- | [[Category: Osipiuk, J | + | [[Category: Osipiuk, J]] |
- | [[Category: Stam, J | + | [[Category: Stam, J]] |
[[Category: Amino-acid biosynthesis]] | [[Category: Amino-acid biosynthesis]] | ||
- | [[Category: Center for structural genomics of infectious disease]] | ||
[[Category: Csgid]] | [[Category: Csgid]] | ||
[[Category: Diaminopimelate biosynthesis]] | [[Category: Diaminopimelate biosynthesis]] | ||
- | [[Category: Dihydrodipicolinate synthase]] | ||
[[Category: Idp01004]] | [[Category: Idp01004]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
[[Category: Lysine biosynthesis]] | [[Category: Lysine biosynthesis]] | ||
[[Category: Schiff base]] | [[Category: Schiff base]] | ||
- | [[Category: Structural genomic]] |
Revision as of 12:52, 5 January 2015
Dihydrodipicolinate synthase from Salmonella typhimurium LT2
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Categories: Dihydrodipicolinate synthase | Salmonella enterica subsp. enterica serovar typhimurium str. lt2 | Anderson, W F | Structural genomic | Joachimiak, A | Maltseva, N | Osipiuk, J | Stam, J | Amino-acid biosynthesis | Csgid | Diaminopimelate biosynthesis | Idp01004 | Lyase | Lysine biosynthesis | Schiff base