1mke

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1mke]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MKE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MKE FirstGlance]. <br>
<table><tr><td colspan='2'>[[1mke]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MKE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MKE FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mke OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mke RCSB], [http://www.ebi.ac.uk/pdbsum/1mke PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mke OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mke RCSB], [http://www.ebi.ac.uk/pdbsum/1mke PDBsum]</span></td></tr>
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<table>
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</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/WIPF1_HUMAN WIPF1_HUMAN]] Defects in WIPF1 are the cause of Wiskott-Aldrich syndrome type 2 (WAS2) [MIM:[http://omim.org/entry/614493 614493]]. WAS2 is an immunodeficiency disorder characterized by eczema, thrombocytopenia, recurrent infections, defective T-cell proliferation, and impaired natural killer cell function.<ref>PMID:22231303</ref>
[[http://www.uniprot.org/uniprot/WIPF1_HUMAN WIPF1_HUMAN]] Defects in WIPF1 are the cause of Wiskott-Aldrich syndrome type 2 (WAS2) [MIM:[http://omim.org/entry/614493 614493]]. WAS2 is an immunodeficiency disorder characterized by eczema, thrombocytopenia, recurrent infections, defective T-cell proliferation, and impaired natural killer cell function.<ref>PMID:22231303</ref>
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</StructureSection>
</StructureSection>
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Lim, W A.]]
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[[Category: Lim, W A]]
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[[Category: Peterson, F C.]]
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[[Category: Peterson, F C]]
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[[Category: Prehoda, K E.]]
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[[Category: Prehoda, K E]]
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[[Category: Scott, J A.]]
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[[Category: Scott, J A]]
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[[Category: Volkman, B F.]]
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[[Category: Volkman, B F]]
[[Category: Polyproline]]
[[Category: Polyproline]]
[[Category: Protein binding]]
[[Category: Protein binding]]
[[Category: Protein-protein complex]]
[[Category: Protein-protein complex]]

Revision as of 15:42, 5 January 2015

Structure of the N-WASP EVH1 Domain-WIP complex

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