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1njj

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1njj]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_gambiense Trypanosoma brucei gambiense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NJJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[1njj]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_gambiense Trypanosoma brucei gambiense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NJJ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GET:GENETICIN'>GET</scene>, <scene name='pdbligand=ORX:N~2~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-D-ORNITHINE'>ORX</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GET:GENETICIN'>GET</scene>, <scene name='pdbligand=ORX:N~2~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-D-ORNITHINE'>ORX</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1qu4|1qu4]], [[1f3t|1f3t]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1qu4|1qu4]], [[1f3t|1f3t]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ornithine_decarboxylase Ornithine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.17 4.1.1.17] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ornithine_decarboxylase Ornithine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.17 4.1.1.17] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1njj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1njj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1njj RCSB], [http://www.ebi.ac.uk/pdbsum/1njj PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1njj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1njj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1njj RCSB], [http://www.ebi.ac.uk/pdbsum/1njj PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Ornithine decarboxylase]]
[[Category: Ornithine decarboxylase]]
[[Category: Trypanosoma brucei gambiense]]
[[Category: Trypanosoma brucei gambiense]]
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[[Category: Goldsmith, E J.]]
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[[Category: Goldsmith, E J]]
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[[Category: Jackson, L K.]]
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[[Category: Jackson, L K]]
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[[Category: Phillips, M A.]]
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[[Category: Phillips, M A]]
[[Category: D-ornithine]]
[[Category: D-ornithine]]
[[Category: G418]]
[[Category: G418]]
[[Category: Lyase]]
[[Category: Lyase]]
[[Category: Odc]]
[[Category: Odc]]
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[[Category: Ornithine decarboxylase]]
 
[[Category: Plp]]
[[Category: Plp]]
[[Category: Pyridoxal 5'-phosphate]]
[[Category: Pyridoxal 5'-phosphate]]

Revision as of 16:21, 5 January 2015

Crystal structure determination of T. brucei ornithine decarboxylase bound to D-ornithine and to G418

1njj, resolution 2.45Å

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