This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1rl4
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1rl4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_3d7 Plasmodium falciparum 3d7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RL4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RL4 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1rl4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_3d7 Plasmodium falciparum 3d7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RL4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RL4 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BL5:2-{N-[2-(5-AMINO-1-PHENYLCARBAMOYL-PENTYLCARBAMOYL)-HEXYL]-HYDRAZINOMETHYL}-HEXANOIC+ACID(5-AMINO-1-PHENYLCARBAMOYL-PENTYL)-AMIDE'>BL5</scene>, <scene name='pdbligand=BRR:(2R)-2-{[FORMYL(HYDROXY)AMINO]METHYL}HEXANOIC+ACID'>BRR</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BL5:2-{N-[2-(5-AMINO-1-PHENYLCARBAMOYL-PENTYLCARBAMOYL)-HEXYL]-HYDRAZINOMETHYL}-HEXANOIC+ACID(5-AMINO-1-PHENYLCARBAMOYL-PENTYL)-AMIDE'>BL5</scene>, <scene name='pdbligand=BRR:(2R)-2-{[FORMYL(HYDROXY)AMINO]METHYL}HEXANOIC+ACID'>BRR</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jym|1jym]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jym|1jym]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 Plasmodium falciparum 3D7])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 Plasmodium falciparum 3D7])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Formylmethionine_deformylase Formylmethionine deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.31 3.5.1.31] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Formylmethionine_deformylase Formylmethionine deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.31 3.5.1.31] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rl4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rl4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rl4 RCSB], [http://www.ebi.ac.uk/pdbsum/1rl4 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rl4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rl4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rl4 RCSB], [http://www.ebi.ac.uk/pdbsum/1rl4 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 33: | Line 33: | ||
[[Category: Formylmethionine deformylase]] | [[Category: Formylmethionine deformylase]] | ||
[[Category: Plasmodium falciparum 3d7]] | [[Category: Plasmodium falciparum 3d7]] | ||
| - | [[Category: Hirsh, I | + | [[Category: Hirsh, I]] |
| - | [[Category: Hol, W G.J | + | [[Category: Hol, W G.J]] |
| - | [[Category: Kumar, A | + | [[Category: Kumar, A]] |
| - | [[Category: Nguyen, K T | + | [[Category: Nguyen, K T]] |
| - | [[Category: Pei, D | + | [[Category: Pei, D]] |
| - | [[Category: Robien, M A | + | [[Category: Robien, M A]] |
| - | [[Category: Turley, S | + | [[Category: Turley, S]] |
[[Category: Crystal engineering]] | [[Category: Crystal engineering]] | ||
[[Category: Drug design]] | [[Category: Drug design]] | ||
Revision as of 07:11, 6 January 2015
Plasmodium falciparum peptide deformylase complex with inhibitor
| |||||||||||
