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1rcj
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1rcj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RCJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RCJ FirstGlance]. <br> | <table><tr><td colspan='2'>[[1rcj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RCJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RCJ FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MA4:CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE'>MA4</scene>, <scene name='pdbligand=TBI:TAZOBACTAM+TRANS-ENAMINE+INTERMEDIATE'>TBI</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MA4:CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE'>MA4</scene>, <scene name='pdbligand=TBI:TAZOBACTAM+TRANS-ENAMINE+INTERMEDIATE'>TBI</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1g56|1g56]], [[1n9b|1n9b]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1g56|1g56]], [[1n9b|1n9b]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BLA, SHV1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 Klebsiella pneumoniae])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BLA, SHV1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 Klebsiella pneumoniae])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rcj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rcj RCSB], [http://www.ebi.ac.uk/pdbsum/1rcj PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rcj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rcj RCSB], [http://www.ebi.ac.uk/pdbsum/1rcj PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Beta-lactamase]] | [[Category: Beta-lactamase]] | ||
[[Category: Klebsiella pneumoniae]] | [[Category: Klebsiella pneumoniae]] | ||
| - | [[Category: Akker, F van den | + | [[Category: Akker, F van den]] |
| - | [[Category: Bonomo, R A | + | [[Category: Bonomo, R A]] |
| - | [[Category: Carey, M P | + | [[Category: Carey, M P]] |
| - | [[Category: Carey, P R | + | [[Category: Carey, P R]] |
| - | [[Category: Helfand, M S | + | [[Category: Helfand, M S]] |
| - | [[Category: Hujer, A M | + | [[Category: Hujer, A M]] |
| - | [[Category: Padayatti, P S | + | [[Category: Padayatti, P S]] |
| - | [[Category: Totir, M A | + | [[Category: Totir, M A]] |
[[Category: Beta-lactam hydrolase]] | [[Category: Beta-lactam hydrolase]] | ||
| - | [[Category: Beta-lactamase]] | ||
[[Category: Covalent intermediate]] | [[Category: Covalent intermediate]] | ||
[[Category: Detergent binding]] | [[Category: Detergent binding]] | ||
Revision as of 08:07, 6 January 2015
Crystal structure of E166A mutant of SHV-1 beta-lactamase with the trans-enamine intermediate of tazobactam
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