2idy
From Proteopedia
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| - | [[Image:2idy.gif|left|200px]] | + | [[Image:2idy.gif|left|200px]] |
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| - | '''NMR Structure of the SARS-CoV non-structural protein nsp3a''' | + | {{Structure |
| + | |PDB= 2idy |SIZE=350|CAPTION= <scene name='initialview01'>2idy</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''NMR Structure of the SARS-CoV non-structural protein nsp3a''' | ||
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==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2IDY is a [ | + | 2IDY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sars_coronavirus Sars coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IDY OCA]. |
==Reference== | ==Reference== | ||
| - | Nuclear magnetic resonance structure of the N-terminal domain of nonstructural protein 3 from the severe acute respiratory syndrome coronavirus., Serrano P, Johnson MA, Almeida MS, Horst R, Herrmann T, Joseph JS, Neuman BW, Subramanian V, Saikatendu KS, Buchmeier MJ, Stevens RC, Kuhn P, Wuthrich K, J Virol. 2007 Nov;81(21):12049-60. Epub 2007 Aug 29. PMID:[http:// | + | Nuclear magnetic resonance structure of the N-terminal domain of nonstructural protein 3 from the severe acute respiratory syndrome coronavirus., Serrano P, Johnson MA, Almeida MS, Horst R, Herrmann T, Joseph JS, Neuman BW, Subramanian V, Saikatendu KS, Buchmeier MJ, Stevens RC, Kuhn P, Wuthrich K, J Virol. 2007 Nov;81(21):12049-60. Epub 2007 Aug 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17728234 17728234] |
[[Category: Sars coronavirus]] | [[Category: Sars coronavirus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: Wuthrich, K.]] | [[Category: Wuthrich, K.]] | ||
[[Category: jcsg]] | [[Category: jcsg]] | ||
| - | [[Category: joint center for structural | + | [[Category: joint center for structural genomic]] |
[[Category: protein structure initiative]] | [[Category: protein structure initiative]] | ||
[[Category: psi-2]] | [[Category: psi-2]] | ||
[[Category: sars coronavirus nmr nsp3a]] | [[Category: sars coronavirus nmr nsp3a]] | ||
| - | [[Category: structural | + | [[Category: structural genomic]] |
[[Category: viral protein]] | [[Category: viral protein]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:28:23 2008'' |
Revision as of 15:28, 20 March 2008
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
NMR Structure of the SARS-CoV non-structural protein nsp3a
Overview
This paper describes the structure determination of nsp3a, the N-terminal domain of the severe acute respiratory syndrome coronavirus (SARS-CoV) nonstructural protein 3. nsp3a exhibits a ubiquitin-like globular fold of residues 1 to 112 and a flexibly extended glutamic acid-rich domain of residues 113 to 183. In addition to the four beta-strands and two alpha-helices that are common to ubiquitin-like folds, the globular domain of nsp3a contains two short helices representing a feature that has not previously been observed in these proteins. Nuclear magnetic resonance chemical shift perturbations showed that these unique structural elements are involved in interactions with single-stranded RNA. Structural similarities with proteins involved in various cell-signaling pathways indicate possible roles of nsp3a in viral infection and persistence.
About this Structure
2IDY is a Single protein structure of sequence from Sars coronavirus. Full crystallographic information is available from OCA.
Reference
Nuclear magnetic resonance structure of the N-terminal domain of nonstructural protein 3 from the severe acute respiratory syndrome coronavirus., Serrano P, Johnson MA, Almeida MS, Horst R, Herrmann T, Joseph JS, Neuman BW, Subramanian V, Saikatendu KS, Buchmeier MJ, Stevens RC, Kuhn P, Wuthrich K, J Virol. 2007 Nov;81(21):12049-60. Epub 2007 Aug 29. PMID:17728234
Page seeded by OCA on Thu Mar 20 17:28:23 2008
Categories: Sars coronavirus | Single protein | Almeida, M S. | Herrmann, T. | Horst, R. | JCSG, Joint Center for Structural Genomics. | Johnson, M A. | Joseph, J. | Kuhn, P. | Saikatendu, K. | Serrano, P. | Stevens, R C. | Subramanian, V. | Wuthrich, K. | Jcsg | Joint center for structural genomic | Protein structure initiative | Psi-2 | Sars coronavirus nmr nsp3a | Structural genomic | Viral protein
