2if4

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[[Image:2if4.gif|left|200px]]<br /><applet load="2if4" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2if4.gif|left|200px]]
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caption="2if4, resolution 2.85&Aring;" />
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'''Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana'''<br />
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{{Structure
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|PDB= 2if4 |SIZE=350|CAPTION= <scene name='initialview01'>2if4</scene>, resolution 2.85&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE= FKBP42, TWD1, UCU2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 Arabidopsis thaliana])
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}}
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'''Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2IF4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IF4 OCA].
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2IF4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IF4 OCA].
==Reference==
==Reference==
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Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana: a paradigm for regulation of plant ABC transporters., Granzin J, Eckhoff A, Weiergraber OH, J Mol Biol. 2006 Dec 8;364(4):799-809. Epub 2006 Sep 26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17045295 17045295]
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Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana: a paradigm for regulation of plant ABC transporters., Granzin J, Eckhoff A, Weiergraber OH, J Mol Biol. 2006 Dec 8;364(4):799-809. Epub 2006 Sep 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17045295 17045295]
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: tpr-like]]
[[Category: tpr-like]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:51:58 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:28:45 2008''

Revision as of 15:28, 20 March 2008


PDB ID 2if4

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, resolution 2.85Å
Gene: FKBP42, TWD1, UCU2 (Arabidopsis thaliana)
Coordinates: save as pdb, mmCIF, xml



Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana


Overview

FKBP42 is a membrane-anchored immunophilin playing a critical role in morphogenesis and development of higher plants. We present the X-ray structure of the cytoplasmic portion of FKBP42 comprising both the FKBP-like domain and the TPR domain at 2.85 A resolution. The data shed light on the probable binding modes of key interaction partners, including HSP90 and two classes of ABC transporters. The resulting models provide a structural background for further investigation of the unique biological properties of this protein.

About this Structure

2IF4 is a Single protein structure of sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

Reference

Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana: a paradigm for regulation of plant ABC transporters., Granzin J, Eckhoff A, Weiergraber OH, J Mol Biol. 2006 Dec 8;364(4):799-809. Epub 2006 Sep 26. PMID:17045295

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