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2amf

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2amf]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes_m1_gas Streptococcus pyogenes m1 gas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AMF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AMF FirstGlance]. <br>
<table><tr><td colspan='2'>[[2amf]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes_m1_gas Streptococcus pyogenes m1 gas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AMF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AMF FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PRO:PROLINE'>PRO</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PRO:PROLINE'>PRO</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yqg|1yqg]], [[2ag8|2ag8]], [[2ahr|2ahr]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yqg|1yqg]], [[2ag8|2ag8]], [[2ahr|2ahr]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">proC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=160490 Streptococcus pyogenes M1 GAS])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">proC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=160490 Streptococcus pyogenes M1 GAS])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(NAD(P)(+)) Aldehyde dehydrogenase (NAD(P)(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.5 1.2.1.5] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(NAD(P)(+)) Aldehyde dehydrogenase (NAD(P)(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.5 1.2.1.5] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2amf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2amf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2amf RCSB], [http://www.ebi.ac.uk/pdbsum/2amf PDBsum], [http://www.topsan.org/Proteins/MCSG/2amf TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2amf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2amf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2amf RCSB], [http://www.ebi.ac.uk/pdbsum/2amf PDBsum], [http://www.topsan.org/Proteins/MCSG/2amf TOPSAN]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Streptococcus pyogenes m1 gas]]
[[Category: Streptococcus pyogenes m1 gas]]
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[[Category: Holzle, D.]]
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[[Category: Holzle, D]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak, A]]
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[[Category: Lezondra, L.]]
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[[Category: Lezondra, L]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Structural genomic]]
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[[Category: Nocek, B.]]
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[[Category: Nocek, B]]
[[Category: 1-pyrroline-5-reductase]]
[[Category: 1-pyrroline-5-reductase]]
[[Category: Domain swapping]]
[[Category: Domain swapping]]
[[Category: Human pathogen]]
[[Category: Human pathogen]]
[[Category: Mcsg]]
[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
 
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Proline biosynthesis]]
[[Category: Proline biosynthesis]]
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[[Category: Protein structure initiative]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Pyrroline reductase]]
[[Category: Pyrroline reductase]]
[[Category: Pyrroline-5-carboxylate reductase]]
[[Category: Pyrroline-5-carboxylate reductase]]
[[Category: Rossmann fold]]
[[Category: Rossmann fold]]
[[Category: Streptococcus pyogene]]
[[Category: Streptococcus pyogene]]
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[[Category: Structural genomic]]
 

Revision as of 10:42, 8 January 2015

Crystal structure of 1-Pyrroline-5-Carboxylate Reductase from Human Pathogen Streptococcus Pyogenes

2amf, resolution 2.20Å

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