2j96
From Proteopedia
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| - | [[Image:2j96.gif|left|200px]] | + | [[Image:2j96.gif|left|200px]] |
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| - | '''THE E-CONFIGURATION OF ALFA-PHYCOERYTHROCYANIN''' | + | {{Structure |
| + | |PDB= 2j96 |SIZE=350|CAPTION= <scene name='initialview01'>2j96</scene>, resolution 2.25Å | ||
| + | |SITE= <scene name='pdbsite=AC1:Pvn+Binding+Site+For+Chain+B'>AC1</scene> | ||
| + | |LIGAND= <scene name='pdbligand=PVN:PHYCOVIOLOBILIN'>PVN</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''THE E-CONFIGURATION OF ALFA-PHYCOERYTHROCYANIN''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2J96 is a [ | + | 2J96 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mastigocladus_laminosus Mastigocladus laminosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J96 OCA]. |
==Reference== | ==Reference== | ||
| - | Structural basis for the photochemistry of alpha-phycoerythrocyanin., Schmidt M, Patel A, Zhao Y, Reuter W, Biochemistry. 2007 Jan 16;46(2):416-23. PMID:[http:// | + | Structural basis for the photochemistry of alpha-phycoerythrocyanin., Schmidt M, Patel A, Zhao Y, Reuter W, Biochemistry. 2007 Jan 16;46(2):416-23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17209552 17209552] |
[[Category: Mastigocladus laminosus]] | [[Category: Mastigocladus laminosus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: light harvesting]] | [[Category: light harvesting]] | ||
[[Category: photosynthesis]] | [[Category: photosynthesis]] | ||
| - | [[Category: | + | [[Category: phycobiliprotein]] |
[[Category: phycobilisome]] | [[Category: phycobilisome]] | ||
[[Category: transport]] | [[Category: transport]] | ||
[[Category: z- to e-isomerization]] | [[Category: z- to e-isomerization]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:38:53 2008'' |
Revision as of 15:38, 20 March 2008
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| , resolution 2.25Å | |||||||
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
THE E-CONFIGURATION OF ALFA-PHYCOERYTHROCYANIN
Overview
Phycobiliproteins and phytochromes are light-harvesting and light-sensing proteins containing linear tetrapyrroles, so-called bile chromophores. The chromophores in certain biliproteins, including the phytochromes, isomerize reversibly from a stable Z-configuration to a stable E-configuration when irradiated with light of the appropriate wavelength. Here, we report the crystal structure of alpha-phycoerythrocyanin with its chromophore in the E-configuration, compare it with the Z-configuration found in trimeric phycoerythrocyanin, and reveal the structural bases of the isomerization. The geometric changes of the chromophore account for the large spectral shift, which characterizes the overall transition. Interactions of the chromophore A and D pyrrole rings with flexible protein moieties are required for the formation and stabilization of the isomers. We predict that the results will hold for all photoactive biliproteins.
About this Structure
2J96 is a Single protein structure of sequence from Mastigocladus laminosus. Full crystallographic information is available from OCA.
Reference
Structural basis for the photochemistry of alpha-phycoerythrocyanin., Schmidt M, Patel A, Zhao Y, Reuter W, Biochemistry. 2007 Jan 16;46(2):416-23. PMID:17209552
Page seeded by OCA on Thu Mar 20 17:38:53 2008
