4qxl
From Proteopedia
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| - | ''' | + | ==Crystal Structure of FLHE== |
| + | <StructureSection load='4qxl' size='340' side='right' caption='[[4qxl]], [[Resolution|resolution]] 1.51Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4qxl]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QXL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QXL FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qxl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qxl RCSB], [http://www.ebi.ac.uk/pdbsum/4qxl PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The bacterial flagellum is assembled by a multicomponent transport apparatus categorized as a Type III secretion (T3S) system. The secretion of proteins that assemble into the flagellum is driven by the proton motive force. The periplasmic protein FlhE is a member of the flhBAE operon in the majority of bacteria where FlhE is found. FlhA and FlhB are established components of the flagellar T3S system. The absence of FlhE results in a proton leak through the flagellar system, inappropriate secretion patterns, and cell death, indicating that FlhE regulates an important aspect of proper flagellar biosynthesis. We isolated FlhE from the periplasm of Salmonella and solved its structure to 1.5A resolution. Possible roles of FlhE, including that of a chaperone, are discussed. | ||
| - | + | Structure of Salmonella FlhE, conserved member of a flagellar Type III secretion operon.,Lee J, Monzingo AF, Keatinge-Clay AT, Harshey RM J Mol Biol. 2014 Dec 26. pii: S0022-2836(14)00647-0. doi:, 10.1016/j.jmb.2014.11.022. PMID:25545591<ref>PMID:25545591</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Harshey, R M]] | ||
| + | [[Category: Keatinge-Clay, A T]] | ||
[[Category: Lee, J]] | [[Category: Lee, J]] | ||
| - | [[Category: | + | [[Category: Monzingo, A F]] |
| - | [[Category: | + | [[Category: Beta-sandwich]] |
| - | [[Category: | + | [[Category: Flagellar type iii secretion system]] |
| + | [[Category: Motor protein]] | ||
| + | [[Category: Periplasmic]] | ||
| + | [[Category: Secretion pore plug]] | ||
Revision as of 13:35, 14 January 2015
Crystal Structure of FLHE
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